Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 1/20 | 0.36 |
| ▸ | CA2 | P00918 | 1/20 | 0.36 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.33 |
| ▸ | SLC9A1 | P19634 | 5/20 | 0.33 |
| ▸ | NUDT1 | P36639 | 1/20 | 0.33 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.33 |
| ▸ | KMO | O15229 | 1/20 | 0.32 |
| ▸ | KAT6A | Q92794 | 1/20 | 0.32 |
| ▸ | PGR | P06401 | 1/20 | 0.32 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.31 |
| ▸ | PDE4A | P27815 | 1/20 | 0.31 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.31 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.31 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL309222 | 0.62 | ALDH1A1 (0.52) | CA1CA2ALOX5TAAR1KAT6A | |
| SCHEMBL10459345 | 0.62 | CHRM1 (0.51) | ALOX5SLC9A1KAT6APGRRAB9A | |
| SCHEMBL307761 | 0.61 | ALOX5 (0.53) | CA1CA2ALOX5TAAR1KAT6A | |
| Sulfamate SCHEMBL27561942 | 0.60 | PARP1 (0.52) | CA1CA2ALOX5PGRTSHR | |
| SCHEMBL817554 | 0.59 | ALOX5 (0.65) | ALOX5TAAR1PGRESR2NPC1 | |
| SCHEMBL31222672 | 0.59 | ALOX5 (0.65) | ALOX5TAAR1PGRESR2NPC1 | |
| SCHEMBL10808374 | 0.58 | TSHR (0.52) | ALOX5PGRNPC1TSHRRAB9A | |
| SCHEMBL4603856 | 0.58 | ALOX5 (0.38) | ALOX5NUDT1TAAR1KMOPGR | |
| SCHEMBL22587920 | 0.58 | PTGES2 (0.50) | CA1CA2NPC1RAB9ACHRM1 | |
| SCHEMBL29629014 | 0.57 | ALOX5 (0.62) | ALOX5TAAR1PGRESR2NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4892968-A | 3,3'-Dichloro-4,4-diaminodiphenyl sulfonic acids | CIBA-GEIGY CORPORATION (US) | 1990-01-09 | — | — | US | disclosed |