SCHEMBL4603856

SCHEMBL4603856

OC1(O)C=CC(c2cccc(Cl)c2)=CC1Cl

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALOX5 P09917 1/20 0.38
NOTUM Q6P988 1/20 0.37
ESR2 Q92731 1/20 0.35
IDO1 P14902 3/20 0.34
PDK2 Q15119 1/20 0.34
HRH1 P35367 1/20 0.33
TAAR1 Q96RJ0 1/20 0.33
PGR P06401 2/20 0.33
CNR2 P34972 1/20 0.33
KMO O15229 1/20 0.33
DYRK3 O43781 1/20 0.33
CCNT1 O60563 1/20 0.33
CCNA2 P20248 1/20 0.33
CDK2 P24941 1/20 0.33
CDK9 P50750 1/20 0.33
CDK5 Q00535 1/20 0.33
DYRK1A Q13627 1/20 0.33
CDK5R1 Q15078 1/20 0.33
DYRK2 Q92630 1/20 0.33
DYRK1B Q9Y463 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1628431 0.83 NOTUM (0.38) ALOX5NOTUMIDO1HRH1TAAR1
SCHEMBL10410660 0.71 ALDH1A1 (0.37) NOTUMTDO2
Hydrochloric Acid SCHEMBL10800694 0.65 MAOA (0.38) TSHRNPC1RAB9A
SCHEMBL817554 0.64 ALOX5 (0.65) ALOX5NOTUMESR2IDO1TAAR1
SCHEMBL31222672 0.64 ALOX5 (0.65) ALOX5NOTUMESR2IDO1TAAR1
SCHEMBL21091939 0.62 PGR (0.38) ALOX5NOTUMESR2IDO1PGR
SCHEMBL29629014 0.62 ALOX5 (0.62) ALOX5NOTUMESR2IDO1TAAR1
Hydrochloric Acid SCHEMBL28332867 0.62 ALOX5 (0.62) ALOX5NOTUMESR2IDO1TAAR1
Hydrochloric Acid SCHEMBL31070804 0.62 ALOX5 (0.62) ALOX5NOTUMESR2IDO1TAAR1
SCHEMBL28994669 0.61 ALOX5 (0.61) ALOX5NOTUMESR2IDO1TAAR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 29 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1940913-A2 METHODS FOR PREPARING TRANSPARENT ARTICLES FROM BIPHENOL POLYCARBONATE COPOLYMERS General Electric Company (US) 2008-07-09 EP disclosed
WO-2007053327-A2 METHODS FOR PREPARING TRANSPARENT ARTICLES FROM BIPHENOL POLYCARBONATE COPOLYMERS GENERAL ELECTRIC COMPANY (US) 2007-05-10 WO disclosed
US-6323302-B1 SUPPLYING AROMATIC DIHYDROXY COMPOUND POWDER AND A CARBONIC ACID DIESTER INTO MELTING VESSEL THROUGH A TRANSPORTATION PIPING; MIXING MELTING; INITIATING MELT POLYMERIZATION IN PRESENCE OR ABSENCE OF CATALYST TEIJIN LIMITED (JP) 2001-11-27 US disclosed
EP-0700532-B1 ALIGNMENT LAYER FOR LIQUID CRYSTALS AVENTIS RES & TECH GMBH & CO (DE) 2000-03-29 EP disclosed
US-5744203-A POLYMER MIXTURES OF POLYURETHANES, POLYESTERS, POLYIMIDES, POLYCARBONATES AND POLYUREAS HOECHST AKTIENGESELLSCHAFT (DE) 1998-04-28 US disclosed
US-5670084-A Alignment layer material for liquid crystal display devices HOECHST AKTIENGESELLSCHAFT (DE) 1997-09-23 US disclosed
EP-0708149-A1 Alignment layer material for liquid crystal display devices HOECHST AKTIENGESELLSCHAFT (DE) 1996-04-24 EP disclosed
EP-0700532-A1 ALIGNMENT LAYER FOR LIQUID CRYSTALS HOECHST AKTIENGESELLSCHAFT (DE) 1996-03-13 EP disclosed
WO-1994028458-A1 ALIGNMENT LAYER FOR LIQUID CRYSTALS HOECHST AKTIENGESELLSCHAFT (DE) 1994-12-08 WO disclosed
US-4983648-A Molded objects; polycarbonate and/or aromatic polyester carbonate, additive, rubbery polymer as concentrate resin; let-down resin for dispersing concentrate resin; melt combining in molding machine THE DOW CHEMICAL COMPANY (US) 1991-01-08 US disclosed
US-4349658-A Flame retardant aromatic polyester-carbonate copolymer compositions GENERAL ELECTRIC COMPANY (US) 1982-09-14 US disclosed
WO-1982002401-A1 BLENDS OF COPOLYESTER-CARBONATE WITH POLYSULFONE GEN ELECTRIC (US) 1982-07-22 WO disclosed
WO-1982002390-A1 FLAME RETARDANT AROMATIC POLYESTER-CARBONATE COPOLYMER COMPOSITIONS GEN ELECTRIC (US) 1982-07-22 WO disclosed
WO-1982002389-A1 BENZOATE ESTER TERMINATED POLYCARBONATE GEN ELECTRIC (US) 1982-07-22 WO disclosed
US-4335039-A DIOXANE PHOSPHITE STABILIZER GENERAL ELECTRIC COMPANY (US) 1982-06-15 US disclosed
US-4276233-A THERMAL STABILIZERS FOR POLYCARBONATES GENERAL ELECTRIC COMPANY (US) 1981-06-30 US disclosed
US-4247448-A POLYVINYL CHLORIDE, POLYESTERS, POLYOLEFINS GENERAL ELECTRIC COMPANY (US) 1981-01-27 US disclosed
US-4240968-A CONCENTRATION OF CHROMAN I FROM A SLURRY GENERAL ELECTRIC COMPANY (US) 1980-12-23 US disclosed
US-4238597-A Process for producing copolyester-carbonates GENERAL ELECTRIC COMPANY (US) 1980-12-09 US disclosed
US-4238596-A Process for obtaining copolyester-carbonates GENERAL ELECTRIC COMPANY (US) 1980-12-09 US disclosed