Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NUDT1 | P36639 | 1/20 | 0.60 |
| ▸ | BACE1 | P56817 | 1/20 | 0.60 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.49 |
| ▸ | THRB | P10828 | 3/20 | 0.47 |
| ▸ | THRA | P10827 | 2/20 | 0.47 |
| ▸ | PDE5A | O76074 | 7/20 | 0.42 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.40 |
| ▸ | ACMSD | Q8TDX5 | 2/20 | 0.38 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.36 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.36 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.36 |
| ▸ | ERCC1 | P07992 | 1/20 | 0.36 |
| ▸ | ERCC4 | Q92889 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL77906 | 0.83 | NUDT1 (0.42) | NUDT1BACE1HSP90AA1THRBTHRA | |
| SCHEMBL10597858 | 0.80 | BACE1 (0.81) | NUDT1BACE1HSP90AA1THRBTHRA | |
| SCHEMBL7182409 | 0.80 | NUDT1 (0.71) | NUDT1BACE1HSP90AA1THRBTHRA | |
| SCHEMBL27749308 | 0.79 | NUDT1 (0.69) | NUDT1BACE1HSP90AA1THRBTHRA | |
| SCHEMBL10596917 | 0.78 | NUDT1 (0.77) | NUDT1BACE1HSP90AA1THRBTHRA | |
| SCHEMBL13586652 | 0.78 | NUDT1 (0.67) | NUDT1BACE1HSP90AA1THRBTHRA | |
| SCHEMBL10595253 | 0.78 | NUDT1 (0.77) | NUDT1BACE1HSP90AA1THRBTHRA | |
| SCHEMBL7796460 | 0.77 | THRB (0.62) | NUDT1BACE1HSP90AA1THRBTHRA | |
| SCHEMBL10565334 | 0.77 | PDE5A (0.39) | NUDT1BACE1THRBTHRAPDE5A | |
| SCHEMBL10594734 | 0.76 | NUDT1 (0.74) | NUDT1BACE1HSP90AA1THRBTHRA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4923909-A | THIXOTROPIC SLURRYING; PIPES; STABILITY; THERMOPLASTIC OR THERMOSETTING RESIN; LIQUID CARRIER | THE B. F. GOODRICH COMPANY (US) | 1990-05-08 | — | — | US | disclosed |