Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 10/20 | 0.55 |
| ▸ | CA1 | P00915 | 10/20 | 0.55 |
| ▸ | CA2 | P00918 | 10/20 | 0.55 |
| ▸ | CA4 | P22748 | 6/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.54 |
| ▸ | LMNA | P02545 | 1/20 | 0.54 |
| ▸ | GAA | P10253 | 1/20 | 0.54 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.53 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.53 |
| ▸ | TSPO | P30536 | 1/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.51 |
| ▸ | RCE1 | Q9Y256 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 2/20 | 0.49 |
| ▸ | RAB9A | P51151 | 2/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | NPC1 | O15118 | 1/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10399412 | 0.85 | LMNA (0.56) | CA12CA1CA2CA4KDM4E | |
| SCHEMBL6411621 | 0.81 | LMNA (0.50) | CA12CA1CA2CA4KDM4E | |
| SCHEMBL23126336 | 0.80 | RAB9A (0.60) | CA12CA1CA2CA4LMNA | |
| SCHEMBL6433208 | 0.79 | ALDH1A1 (0.64) | LMNAOPRM1TSPOMEN1RAB9A | |
| SCHEMBL4172097 | 0.79 | ALDH1A1 (0.55) | LMNAOPRM1TSPOMEN1RAB9A | |
| SCHEMBL13472619 | 0.77 | ALDH1A1 (0.54) | LMNAOPRM1TSPOMEN1RAB9A | |
| SCHEMBL21153738 | 0.77 | GAA (0.53) | CA12CA1CA2CA4KDM4E | |
| SCHEMBL7228409 | 0.76 | MEN1 (0.61) | CA12CA1CA2CA4LMNA | |
| SCHEMBL14224515 | 0.76 | HDAC1 (0.58) | LMNAGAAOPRM1TSPOMEN1 | |
| SCHEMBL4160271 | 0.76 | REN (0.54) | LMNAOPRM1TSPOMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4977144-A | ADENOSINE AGONISTS | CIBA-GEIGY CORPORATION (US) | 1990-12-11 | — | — | US | disclosed |