Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.52 |
| ▸ | HTT | P42858 | 2/20 | 0.52 |
| ▸ | POLB | P06746 | 1/20 | 0.52 |
| ▸ | TSHR | P16473 | 1/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.51 |
| ▸ | PLA2G2A | P14555 | 16/20 | 0.50 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.50 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
| ▸ | HTR6 | P50406 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4541878 | 0.92 | ALDH1A1 (0.53) | ALDH1A1HTTPOLBTSHRMAPK1 | |
| SCHEMBL4375652 | 0.88 | ALDH1A1 (0.50) | ALDH1A1TSHRMAPK1KMT2APLA2G2A | |
| SCHEMBL2071948 | 0.85 | GABRA1 (0.54) | ALDH1A1HTTPOLBTSHRMAPK1 | |
| SCHEMBL8356890 | 0.84 | PLA2G2A (0.52) | ALDH1A1POLBKMT2APLA2G2AMAPT | |
| SCHEMBL4378623 | 0.84 | PLA2G2A (0.52) | POLBKMT2APLA2G2ATP53MAPT | |
| SCHEMBL27789954 | 0.83 | CCR2 (0.52) | ALDH1A1HTTTSHRMAPK1KMT2A | |
| SCHEMBL3088631 | 0.83 | P2RX4 (0.54) | ALDH1A1HTTPOLBMAPK1KMT2A | |
| SCHEMBL8354114 | 0.83 | ALDH1A1 (0.49) | ALDH1A1HTTPOLBTSHRMAPK1 | |
| SCHEMBL8356349 | 0.79 | ALDH1A1 (0.46) | ALDH1A1HTTPOLBTSHRMAPK1 | |
| SCHEMBL10399302 | 0.79 | CYP19A1 (0.48) | ALDH1A1HTTTSHRMAPK1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5877202-A | Indole derivatives useful to treat estrogen-related neoplasms and disorders | AVENTISUB II INC. | 1999-03-02 | — | — | US | disclosed |