Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.52 |
| ▸ | MAPT | P10636 | 7/20 | 0.51 |
| ▸ | NPC1 | O15118 | 2/20 | 0.51 |
| ▸ | RAB9A | P51151 | 2/20 | 0.51 |
| ▸ | PKM | P14618 | 1/20 | 0.51 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.51 |
| ▸ | CDK5R1 | Q15078 | 1/20 | 0.51 |
| ▸ | TP53 | P04637 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.49 |
| ▸ | MEN1 | O00255 | 3/20 | 0.49 |
| ▸ | MAOA | P21397 | 1/20 | 0.48 |
| ▸ | MAOB | P27338 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10399371 | 1.00 | L3MBTL1 (0.52) | L3MBTL1MAPTNPC1RAB9APKM | |
| SCHEMBL10399401 | 1.00 | L3MBTL1 (0.52) | L3MBTL1MAPTNPC1RAB9APKM | |
| SCHEMBL10397921 | 0.82 | MAOA (0.52) | L3MBTL1MAPTNPC1RAB9APKM | |
| SCHEMBL10398899 | 0.82 | MAOA (0.52) | L3MBTL1MAPTNPC1RAB9APKM | |
| SCHEMBL10397891 | 0.81 | MAOA (0.51) | L3MBTL1MAPTNPC1RAB9APKM | |
| SCHEMBL10397890 | 0.81 | MAOA (0.51) | L3MBTL1MAPTNPC1RAB9APKM | |
| SCHEMBL22319268 | 0.81 | HPGDS (0.55) | MAPTNPC1RAB9APKMTP53 | |
| SCHEMBL8564034 | 0.81 | ALDH1A1 (0.57) | MAPTALDH1A1HPGDKDM4E | |
| SCHEMBL6419828 | 0.79 | L3MBTL1 (0.52) | L3MBTL1MAPTNPC1RAB9APKM | |
| SCHEMBL6419827 | 0.79 | L3MBTL1 (0.52) | L3MBTL1MAPTNPC1RAB9APKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4975438-A | ANTICOAGULANT | HOFFMANN-LA ROCHE INC. (US) | 1990-12-04 | — | — | US | disclosed |
| EP-0299379-A1 | Pentadienamide PAF-antagonists | F. HOFFMANN-LA ROCHE AG (CH) | 1989-01-18 | — | — | EP | disclosed |
| US-4788206-A | CARDIOVASCULAR DISORDERS, PLATELETS | HOFFMANN-LA ROCHE INC. (US) | 1988-11-29 | — | — | US | disclosed |