Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOS3 | P29474 | 3/20 | 0.42 |
| ▸ | NOS1 | P29475 | 3/20 | 0.42 |
| ▸ | NOS2 | P35228 | 3/20 | 0.42 |
| ▸ | PARP1 | P09874 | 1/20 | 0.37 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.36 |
| ▸ | HRH4 | Q9H3N8 | 2/20 | 0.36 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.36 |
| ▸ | VCP | P55072 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 2/20 | 0.35 |
| ▸ | RAB9A | P51151 | 2/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | DHFR | P00374 | 3/20 | 0.35 |
| ▸ | HRH2 | P25021 | 1/20 | 0.33 |
| ▸ | HRH1 | P35367 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | GABRP | O00591 | 1/20 | 0.32 |
| ▸ | GABRD | O14764 | 1/20 | 0.32 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11745802 | 0.83 | NPC1 (0.44) | NOS3NOS1NOS2NPC1RAB9A | |
| SCHEMBL25467228 | 0.80 | DHFR (0.45) | NOS3NOS1NOS2PARP1VCP | |
| SCHEMBL16919286 | 0.80 | NOS3 (0.41) | NOS3NOS1NOS2PARP1KCNH2 | |
| SCHEMBL10268101 | 0.80 | NOS3 (0.56) | NOS3NOS1NOS2PARP1VCP | |
| SCHEMBL11745099 | 0.79 | SKP2 (0.46) | NOS2NPC1RAB9ASMN1; SMN2TP53 | |
| SCHEMBL18235103 | 0.78 | NOS3 (0.39) | NOS3NOS1NOS2PARP1KCNH2 | |
| SCHEMBL20870211 | 0.78 | NOS3 (0.39) | NOS3NOS1NOS2PARP1KCNH2 | |
| SCHEMBL15109301 | 0.78 | PIK3CD (0.43) | NOS3NOS1NOS2PARP1KCNH2 | |
| SCHEMBL10780675 | 0.78 | CPB2 (0.47) | NOS3NOS1NOS2PARP1KCNH2 | |
| SCHEMBL15907665 | 0.78 | HTT (0.54) | NOS3NOS1NOS2PARP1KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4931487-A | Chain extenders for polyurethanes | DOW CHEMICAL COMPANY | 1990-06-05 | — | — | US | disclosed |