Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 7/20 | 0.35 |
| ▸ | MAPT | P10636 | 6/20 | 0.33 |
| ▸ | NPC1 | O15118 | 5/20 | 0.33 |
| ▸ | RAB9A | P51151 | 5/20 | 0.33 |
| ▸ | MEN1 | O00255 | 3/20 | 0.33 |
| ▸ | TP53 | P04637 | 3/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 5/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | ACHE | P22303 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.31 |
| ▸ | XBP1 | P17861 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9433016 | 0.58 | ACHE (0.47) | SMN1; SMN2MAPTNPC1RAB9AMEN1 | |
| SCHEMBL29071714 | 0.57 | SMN1; SMN2 (0.37) | SMN1; SMN2MAPTNPC1RAB9AMEN1 | |
| SCHEMBL9613271 | 0.57 | LMNA (0.52) | SMN1; SMN2MAPTNPC1RAB9AMEN1 | |
| SCHEMBL197731 | 0.56 | ACHE (0.73) | CYP2C19CYP2C9LMNAALDH1A1HPGD | |
| SCHEMBL18661495 | 0.56 | ACHE (0.73) | CYP2C19CYP2C9LMNAALDH1A1HPGD | |
| SCHEMBL3287696 | 0.56 | ACHE (0.73) | CYP2C19CYP2C9LMNAALDH1A1HPGD | |
| SCHEMBL874376 | 0.56 | ACHE (0.81) | SMN1; SMN2MAPTNPC1RAB9AMEN1 | |
| Benzidine SCHEMBL11211665 | 0.56 | ACHE (0.81) | SMN1; SMN2MAPTNPC1RAB9AMEN1 | |
| SCHEMBL2608098 | 0.56 | ACHE (0.81) | SMN1; SMN2MAPTNPC1RAB9AMEN1 | |
| SCHEMBL12264964 | 0.55 | MEN1 (0.55) | SMN1; SMN2MAPTNPC1RAB9AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4931487-A | Chain extenders for polyurethanes | DOW CHEMICAL COMPANY | 1990-06-05 | — | — | US | disclosed |