⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19006928 | 0.73 | — | — | |
| SCHEMBL6963893 | 0.72 | — | — | |
| SCHEMBL1630764 | 0.72 | CHRNB2 (0.44) | — | |
| SCHEMBL2486077 | 0.72 | CHRNB2 (0.44) | — | |
| SCHEMBL1630761 | 0.72 | CHRNB2 (0.44) | — | |
| SCHEMBL15829953 | 0.71 | — | — | |
| SCHEMBL15829920 | 0.71 | — | — | |
| SCHEMBL13191392 | 0.71 | — | — | |
| SCHEMBL5014594 | 0.69 | — | — | |
| SCHEMBL2845882 | 0.69 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 24 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230286920-A1 | CYCLOOCTYNES FOR CLICK CHEMISTRY | MASSACHUSETTS INST TECHNOLOGY (US) | 2023-09-14 | — | — | US | disclosed |
| US-11673865-B2 | Cyclooctynes for click chemistry | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2023-06-13 | — | — | US | disclosed |
| US-20220402876-A1 | CYCLOOCTYNES FOR CLICK CHEMISTRY | MASSACHUSETTS INSTITUTE OF TECHNOLOGY | 2022-12-22 | — | — | US | disclosed |
| US-11377424-B1 | Cyclooctynes for click chemistry | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2022-07-05 | — | — | US | disclosed |
| US-10676449-B2 | Electronically activated strained alkynes | WISCONSIN ALUMNI RESEARCH FOUNDATION (US) | 2020-06-09 | — | — | US | disclosed |
| US-20190233385-A1 | ELECTRONICALLY ACTIVATED STRAINED ALKYNES | WISCONSIN ALUMNI RESEARCH FOUNDATION | 2019-08-01 | — | — | US | disclosed |
| EP-3004066-B1 | PROCESS FOR PREPARING 4,6-BIS(ARYLOXY)PYRIMIDINE DERIVATIVES | CHEMINOVA AS (DK) | 2018-04-11 | — | — | EP | disclosed |
| EP-2943485-B1 | BICYCLIC AROMATIC CARBOXAMIDE COMPOUNDS USEFUL AS PIM KINASE INHIBITORS | INCYTE HOLDINGS CORP (US) | 2017-09-20 | — | — | EP | disclosed |
| US-9204652-B2 | Antibacterial agent, substrate surface treatment method using the same, antibacterial agent composition, and substrate surface treatment method using the same | CENTRAL GLASS COMPANY, LIMITED (JP) | 2015-12-08 | — | — | US | disclosed |
| EP-2276732-B1 | NOVEL ESTROGEN RECEPTOR LIGANDS | KAROBIO AB (SE) | 2015-05-20 | — | — | EP | disclosed |
| US-8367665-B2 | Estrogen receptor ligands | KARO BIO AB (SE) | 2013-02-05 | — | — | US | disclosed |
| US-20120282641-A1 | METHOD OF IDENTIFYING PEPTIDES | INDIANA UNIVERSITY RESEARCH AND TECHNOLOGY CORPORATION (US) | 2012-11-08 | — | — | US | disclosed |
| US-20110190294-A1 | NOVEL ESTROGEN RECEPTOR LIGANDS | OASMIA PHARMACEUTICAL AB (SE) | 2011-08-04 | — | — | US | disclosed |
| EP-2276732-A1 | NOVEL ESTROGEN RECEPTOR LIGANDS | KARO BIO AB (SE) | 2011-01-26 | — | — | EP | disclosed |
| WO-2010029002-A1 | TRIAZOLE COMPOUNDS, THE USE THEREOF AND PREPARATIONS CONTAINING THESE COMPOUNDS | BASF SE (DE) | 2010-03-18 | — | — | WO | disclosed |
| WO-2009127686-A1 | NOVEL ESTROGEN RECEPTOR LIGANDS | KARO BIO AB (SE) | 2009-10-22 | — | — | WO | disclosed |
| WO-2009124903-A1 | SUBSTITUTED PYRIDAZINYLMETHYL SULFONAMIDES | BASF SE (DE) | 2009-10-15 | — | — | WO | disclosed |
| CN-100537537-C | Fungicidal composition comprising a pyridylethylbenzamide derivative and a compound capable of inhibiting the electron transport of the respiratory chain in phytopathogenic fungal organisms | BAYER CROPSCIENCE SA (FR) | 2009-09-09 | — | — | CN | disclosed |
| CN-1618792-A | Method of producing methoxyimino acetic amide | BAYER AG (DE) | 2005-05-25 | — | — | CN | disclosed |
| CN-1160313-C | Process for preparing methoxyiminoacetamide | — | 2004-08-04 | — | — | CN | disclosed |