Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | ACHE | P22303 | 3/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.48 |
| ▸ | ATM | Q13315 | 1/20 | 0.46 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.46 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.46 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.46 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.46 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.46 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.46 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.46 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.46 |
| ▸ | LPAR1 | Q92633 | 1/20 | 0.46 |
| ▸ | LPAR5 | Q9H1C0 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21400325 | 0.77 | HDAC1 (0.55) | MEN1KMT2AHDAC1HDAC6CHRM2 | |
| SCHEMBL8773484 | 0.77 | HDAC1 (0.61) | MEN1KMT2AKDM4EALDH1A1GAA | |
| SCHEMBL2117209 | 0.76 | LMNA (0.62) | MEN1KMT2AKDM4EALDH1A1NPSR1 | |
| SCHEMBL3662061 | 0.75 | LMNA (0.58) | MEN1KMT2AALDH1A1HDAC1HDAC6 | |
| SCHEMBL2186353 | 0.75 | RCE1 (0.56) | MEN1KMT2AKDM4EALDH1A1HDAC1 | |
| SCHEMBL678725 | 0.75 | L3MBTL1 (0.54) | MEN1KMT2AALDH1A1GAANPSR1 | |
| SCHEMBL8395278 | 0.75 | ACHE (0.67) | MEN1KMT2AACHEALDH1A1HTT | |
| SCHEMBL4073987 | 0.74 | NPC1 (0.64) | MEN1KMT2ASLC6A4 | |
| Hydrochloric Acid SCHEMBL22407358 | 0.74 | MEN1 (0.50) | MEN1KMT2AACHESLC6A4LPAR1 | |
| SCHEMBL16109508 | 0.74 | HDAC1 (0.62) | MEN1KMT2AALDH1A1HTTNPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4977144-A | ADENOSINE AGONISTS | CIBA-GEIGY CORPORATION (US) | 1990-12-11 | — | — | US | disclosed |
| EP-0354180-A2 | Certain imidazo[4,5-b]pyridine derivatives | CIBA-GEIGY AG (CH) | 1990-02-07 | — | — | EP | disclosed |