Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 13/20 | 0.67 |
| ▸ | HTT | P42858 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | ATM | Q13315 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7806527 | 0.81 | ACHE (1.00) | ACHE | |
| SCHEMBL27917801 | 0.81 | ACHE (0.60) | ACHEHTTMEN1KMT2ACYP3A4 | |
| SCHEMBL10099720 | 0.79 | MEN1 (0.62) | ACHEHTTMEN1KMT2ACYP3A4 | |
| SCHEMBL5276311 | 0.79 | ACHE (0.78) | ACHE | |
| SCHEMBL8041935 | 0.76 | ALDH1A1 (0.50) | ACHEHTTMEN1KMT2ACYP3A4 | |
| SCHEMBL10398306 | 0.75 | MEN1 (0.53) | ACHEHTTMEN1KMT2ACYP3A4 | |
| SCHEMBL10399883 | 0.75 | MEN1 (0.50) | ACHEHTTMEN1KMT2AATM | |
| SCHEMBL2069635 | 0.74 | TP53 (0.59) | ACHEHTTMEN1KMT2ACYP3A4 | |
| SCHEMBL6629576 | 0.74 | ALDH1A1 (0.52) | ACHEHTTMEN1KMT2ACYP3A4 | |
| SCHEMBL7808747 | 0.74 | ACHE (1.00) | ACHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5864043-A | CARDIOVASCULAR DISORDERS AND ANGIOTENSIN ANTAGONIST | KARL THOMAE GMBH (DE) | 1999-01-26 | — | — | US | disclosed |
| US-5541229-A | ANGIOITENSIN II ANTAGONIST AS HYPOTENSIVE AGENTS, ANTIISCHEMIC AGENTS AND CARDIOVASCULAR DISORDERS | DR. KARL THOMAE GMBH (DE) | 1996-07-30 | — | — | US | disclosed |