Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.39 |
| ▸ | ITGB3 | P05106 | 4/20 | 0.37 |
| ▸ | ITGA2B | P08514 | 4/20 | 0.37 |
| ▸ | GBA1 | P04062 | 1/20 | 0.35 |
| ▸ | GNAO1 | P09471 | 1/20 | 0.35 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.35 |
| ▸ | TPSAB1 | Q15661 | 1/20 | 0.35 |
| ▸ | TPSD1 | Q9BZJ3 | 1/20 | 0.35 |
| ▸ | TPSG1 | Q9NRR2 | 1/20 | 0.35 |
| ▸ | FAAH | O00519 | 1/20 | 0.33 |
| ▸ | AVPR2 | P30518 | 1/20 | 0.33 |
| ▸ | AVPR1A | P37288 | 1/20 | 0.33 |
| ▸ | ODC1 | P11926 | 1/20 | 0.33 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.32 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.32 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.32 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16623023 | 0.86 | IDO1 (0.39) | HRH3ITGB3ITGA2BGBA1GNAO1 | |
| SCHEMBL1714611 | 0.79 | SIGMAR1 (0.48) | HRH3ODC1ADRB2ADRB1ADRB3 | |
| SCHEMBL1308005 | 0.78 | GNAO1 (0.39) | HRH3ITGB3ITGA2BGNAO1SLC6A4 | |
| SCHEMBL237382 | 0.78 | ITGB3 (0.47) | HRH3ITGB3ITGA2BGBA1GNAO1 | |
| SCHEMBL331124 | 0.78 | HRH3 (0.47) | HRH3ITGB3ITGA2BGBA1GNAO1 | |
| SCHEMBL30014770 | 0.77 | HRH3 (0.38) | HRH3ITGB3ITGA2BGNAO1SLC6A4 | |
| SCHEMBL13077915 | 0.77 | GNAO1 (0.41) | HRH3ITGB3ITGA2BGNAO1SLC6A4 | |
| SCHEMBL8097693 | 0.76 | ITGB3 (0.46) | HRH3ITGB3ITGA2BGBA1GNAO1 | |
| SCHEMBL8728914 | 0.76 | GNAO1 (0.46) | HRH3ITGB3ITGA2BGBA1GNAO1 | |
| SCHEMBL22582330 | 0.76 | GNAO1 (0.46) | HRH3ITGB3ITGA2BGBA1GNAO1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4952689-A | 3-(substituted propylidene)-2-azetidinone derivates for blood platelet aggregation | TAISHO PHARMACEUTICAL CO., LTD. (JP) | 1990-08-28 | — | — | US | disclosed |
| EP-0365364-A2 | 2-Azetidinone derivatives | TAISHO PHARMACEUTICAL CO. LTD (JP) | 1990-04-25 | — | — | EP | disclosed |