Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.38 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.37 |
| ▸ | TPSAB1 | Q15661 | 2/20 | 0.37 |
| ▸ | TPSD1 | Q9BZJ3 | 2/20 | 0.37 |
| ▸ | TPSG1 | Q9NRR2 | 2/20 | 0.37 |
| ▸ | ITGB3 | P05106 | 5/20 | 0.36 |
| ▸ | ITGA2B | P08514 | 5/20 | 0.36 |
| ▸ | GNAO1 | P09471 | 1/20 | 0.34 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.33 |
| ▸ | HTR2A | P28223 | 1/20 | 0.33 |
| ▸ | HTR2C | P28335 | 1/20 | 0.33 |
| ▸ | HTR7 | P34969 | 1/20 | 0.33 |
| ▸ | HTR2B | P41595 | 1/20 | 0.33 |
| ▸ | HTR3A | P46098 | 1/20 | 0.33 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.33 |
| ▸ | HTR4 | Q13639 | 1/20 | 0.33 |
| ▸ | AVPR2 | P30518 | 1/20 | 0.33 |
| ▸ | AVPR1A | P37288 | 1/20 | 0.33 |
| ▸ | FAAH | O00519 | 1/20 | 0.33 |
| ▸ | NAMPT | P43490 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29892104 | 0.81 | TPSAB1 (0.38) | HRH3SLC6A4TPSAB1TPSD1TPSG1 | |
| SCHEMBL27137149 | 0.79 | ITGB3 (0.50) | TPSAB1TPSD1TPSG1ITGB3ITGA2B | |
| SCHEMBL3362157 | 0.78 | NPC1 (0.42) | HRH3SLC6A4TPSAB1TPSD1TPSG1 | |
| SCHEMBL10400656 | 0.77 | HRH3 (0.39) | HRH3SLC6A4TPSAB1TPSD1TPSG1 | |
| SCHEMBL1308005 | 0.77 | GNAO1 (0.39) | HRH3SLC6A4TPSAB1TPSD1TPSG1 | |
| SCHEMBL3020121 | 0.77 | CHRM1 (0.43) | SLC6A4GNAO1SLC6A2HTR2AHTR2C | |
| SCHEMBL2747396 | 0.77 | SLC6A2 (0.34) | SLC6A4SLC6A2HTR2AHTR2CHTR7 | |
| SCHEMBL2747395 | 0.77 | SLC6A2 (0.34) | SLC6A4SLC6A2HTR2AHTR2CHTR7 | |
| SCHEMBL237382 | 0.77 | ITGB3 (0.47) | HRH3SLC6A4TPSAB1TPSD1TPSG1 | |
| SCHEMBL331124 | 0.77 | HRH3 (0.47) | HRH3SLC6A4TPSAB1TPSD1TPSG1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022223034-A1 | SOS1 DEGRADATION AGENT AND PREPARATION METHOD THEREFOR AND APPLICATION THEREOF | 上海领泰生物医药科技有限公司 | 2022-10-27 | — | — | WO | disclosed |
| WO-2022223033-A1 | SOS1 DEGRADING AGENT AND PREPARATION METHOD THEREFOR AND APPLICATION THEREOF | 上海领泰生物医药科技有限公司 | 2022-10-27 | — | — | WO | disclosed |
| WO-2022223039-A1 | SOS1 DEGRADER, PREPARATION METHOD THEREFOR AND APPLICATION THEREOF | 上海领泰生物医药科技有限公司 | 2022-10-27 | — | — | WO | disclosed |