Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 10/20 | 0.35 |
| ▸ | POLB | P06746 | 3/20 | 0.35 |
| ▸ | TP53 | P04637 | 7/20 | 0.34 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.34 |
| ▸ | ACHE | P22303 | 4/20 | 0.33 |
| ▸ | BCHE | P06276 | 3/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | RECQL | P46063 | 1/20 | 0.33 |
| ▸ | CASP6 | P55212 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.33 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | ATM | Q13315 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10401003 | 0.88 | L3MBTL1 (0.38) | HTTSMN1; SMN2L3MBTL1MAPTPOLB | |
| SCHEMBL9539991 | 0.87 | HPGD (0.36) | SMN1; SMN2L3MBTL1MAPTPOLBTP53 | |
| SCHEMBL9536850 | 0.86 | ACHE (0.37) | SMN1; SMN2L3MBTL1MAPTPOLBTP53 | |
| SCHEMBL9536972 | 0.86 | ACHE (0.37) | SMN1; SMN2L3MBTL1MAPTPOLBTP53 | |
| SCHEMBL9540194 | 0.85 | POLB (0.38) | SMN1; SMN2L3MBTL1MAPTPOLBTP53 | |
| SCHEMBL10400945 | 0.83 | MAPT (0.35) | HTTSMN1; SMN2L3MBTL1MAPTPOLB | |
| SCHEMBL10400743 | 0.77 | SMN1; SMN2 (0.39) | SMN1; SMN2L3MBTL1MAPTPOLBTP53 | |
| SCHEMBL10400778 | 0.76 | SMN1; SMN2 (0.40) | KMT2ASMN1; SMN2L3MBTL1MAPTPOLB | |
| SCHEMBL10400133 | 0.76 | SMN1; SMN2 (0.40) | HTTSMN1; SMN2L3MBTL1MAPTPOLB | |
| SCHEMBL10517367 | 0.75 | TP53 (0.39) | KMT2ASMN1; SMN2L3MBTL1MAPTPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4973690-A | PYRIMIDIN-2-YL UREAS, HERBICICES, PLANT GROWTH REGULATORS | CIBA-GEIGY CORPORATION (US) | 1990-11-27 | — | — | US | disclosed |
| EP-0337944-A1 | Ureas | CIBA-GEIGY AG (CH) | 1989-10-18 | — | — | EP | disclosed |