Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 5/20 | 0.37 |
| ▸ | BCHE | P06276 | 4/20 | 0.37 |
| ▸ | GRIN1 | Q05586 | 2/20 | 0.37 |
| ▸ | GRIN2A | Q12879 | 2/20 | 0.37 |
| ▸ | HPGD | P15428 | 2/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.36 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.36 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 6/20 | 0.35 |
| ▸ | POLB | P06746 | 3/20 | 0.35 |
| ▸ | RECQL | P46063 | 1/20 | 0.35 |
| ▸ | CASP6 | P55212 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.35 |
| ▸ | TP53 | P04637 | 5/20 | 0.35 |
| ▸ | EEF2K | O00418 | 2/20 | 0.34 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9536850 | 1.00 | ACHE (0.37) | ACHEBCHEGRIN1GRIN2AHPGD | |
| SCHEMBL9539991 | 0.99 | HPGD (0.36) | ACHEBCHEGRIN1GRIN2AHPGD | |
| SCHEMBL9540194 | 0.97 | POLB (0.38) | ACHEBCHEGRIN1GRIN2AHPGD | |
| SCHEMBL10401003 | 0.90 | L3MBTL1 (0.38) | ACHEBCHEGRIN1GRIN2AHPGD | |
| SCHEMBL10401002 | 0.86 | KMT2A (0.36) | ACHEBCHEGRIN1GRIN2AHPGD | |
| SCHEMBL9538050 | 0.85 | ACHE (0.40) | ACHEBCHEGRIN1GRIN2AHPGD | |
| SCHEMBL10400945 | 0.85 | MAPT (0.35) | ACHEBCHEGRIN1GRIN2AHPGD | |
| SCHEMBL10400778 | 0.81 | SMN1; SMN2 (0.40) | ACHEBCHEGRIN1GRIN2AHPGD | |
| SCHEMBL10400244 | 0.80 | POLB (0.38) | ACHEBCHEGRIN1GRIN2AHPGD | |
| SCHEMBL10401010 | 0.80 | SMN1; SMN2 (0.38) | HPGDNPC1RAB9AL3MBTL1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0337944-B1 | UREAS | CIBA-GEIGY AG (CH) | 1993-07-28 | — | — | EP | disclosed |
| US-4973690-A | PYRIMIDIN-2-YL UREAS, HERBICICES, PLANT GROWTH REGULATORS | CIBA-GEIGY CORPORATION (US) | 1990-11-27 | — | — | US | disclosed |
| EP-0337944-A1 | Ureas | CIBA-GEIGY AG (CH) | 1989-10-18 | — | — | EP | disclosed |