Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TGM2 | P21980 | 3/20 | 0.48 |
| ▸ | AKT1 | P31749 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | GSTO1 | P78417 | 2/20 | 0.39 |
| ▸ | CES1 | P23141 | 2/20 | 0.38 |
| ▸ | HPGD | P15428 | 2/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | DAO | P14920 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8840278 | 0.81 | RAB9A (0.57) | TGM2AKT1ALDH1A1CYP2C9HPGD | |
| SCHEMBL5067711 | 0.79 | F2 (0.50) | ALDH1A1CYP3A4CYP2C19CES1HPGD | |
| SCHEMBL2931801 | 0.71 | AKT1 (0.54) | TGM2AKT1ALDH1A1HPGDALOX15 | |
| SCHEMBL6687668 | 0.71 | TGM2 (0.64) | TGM2AKT1ALDH1A1CYP3A4TDP1 | |
| SCHEMBL31528720 | 0.70 | ALDH1A1 (0.65) | ALDH1A1CYP2C9CYP2C19HPGDKDM4E | |
| SCHEMBL29111221 | 0.70 | TGM2 (0.75) | TGM2ALDH1A1CYP2C19TDP1KDM4E | |
| SCHEMBL27653304 | 0.70 | KMT2A (0.61) | TGM2AKT1ALDH1A1CYP3A4CYP2C9 | |
| SCHEMBL25369963 | 0.69 | TSHR (0.53) | TGM2ALDH1A1CYP2C19MAPK1TDP1 | |
| SCHEMBL7904447 | 0.69 | AKT1 (0.52) | TGM2AKT1ALDH1A1CYP3A4CYP2C9 | |
| SCHEMBL28159745 | 0.69 | KMT2A (0.59) | TGM2AKT1ALDH1A1CYP3A4CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4973554-A | COMPLEXING WITH POLYMER OF ACRYLAMIDE AND N-ACRYLOYL-M-AMINO-BENZAMIDINE | NATIONAL RESEARCH COUNCIL OF CANADA (CA) | 1990-11-27 | — | — | US | claimed |
| US-4973554-A | COMPLEXING WITH POLYMER OF ACRYLAMIDE AND N-ACRYLOYL-M-AMINO-BENZAMIDINE | NATIONAL RESEARCH COUNCIL OF CANADA (CA) | 1990-11-27 | — | — | US | disclosed |