SCHEMBL2931801

SCHEMBL2931801

C=CC(=O)NC(=O)c1ccccc1

nearest known ligand 0.59

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
AKT1 P31749 1/20 0.54
TGM2 P21980 1/20 0.53
ALDH1A1 P00352 3/20 0.52
NPC1 O15118 4/20 0.50
RAB9A P51151 4/20 0.50
MEN1 O00255 1/20 0.50
KMT2A Q03164 1/20 0.50
HDAC3 O15379 1/20 0.50
CA12 O43570 1/20 0.50
CA1 P00915 1/20 0.50
IDO1 P14902 1/20 0.50
ALOX15 P16050 1/20 0.50
HDAC1 Q13547 1/20 0.50
CA9 Q16790 1/20 0.50
HDAC7 Q8WUI4 1/20 0.50
HDAC2 Q92769 1/20 0.50
HSD17B10 Q99714 1/20 0.50
HDAC8 Q9BY41 1/20 0.50
HDAC6 Q9UBN7 1/20 0.50
NCOR2 Q9Y618 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3491749 0.89 RAB9A (0.56) TGM2ALDH1A1NPC1RAB9AMEN1
SCHEMBL15979119 0.84 ALDH1A1 (0.44) AKT1TGM2ALDH1A1NPC1RAB9A
SCHEMBL28375941 0.83 AKT1 (0.54) AKT1TGM2ALDH1A1NPC1RAB9A
SCHEMBL8840278 0.82 RAB9A (0.57) AKT1TGM2ALDH1A1NPC1RAB9A
SCHEMBL7904447 0.82 AKT1 (0.52) AKT1TGM2ALDH1A1MEN1KMT2A
SCHEMBL14837692 0.81 TGM2 (0.50) AKT1TGM2ALDH1A1NPC1RAB9A
SCHEMBL21616630 0.81 ALDH1A1 (0.53) ALDH1A1NPC1RAB9AMEN1KMT2A
SCHEMBL17997805 0.80 LMNA (0.50) ALDH1A1NPC1RAB9AMEN1KMT2A
SCHEMBL7047441 0.80 MAPT (0.52) ALDH1A1NPC1RAB9ALMNAEPHX1
SCHEMBL76489 0.79 ALDH1A1 (0.67) ALDH1A1NPC1RAB9AMEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 44 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115108985-A Synthesis method of 4- (cyclohexylmethyl) -2, 4-dimethylisoquinoline-1, 3(2H, 4H) -diketone 浙江工业大学 2022-09-27 CN claimed
CN-113861240-A Trifluoromethyl reagent and synthesis method and application thereof 中国科学院大学 2021-12-31 CN claimed
US-5618829-A SUPPRESSION GROWTH OF CANCER CELLS MITSUBISHI CHEMICAL CORPORATION (JP) 1997-04-08 US claimed
EP-0608897-A2 Tyrosine kinase inhibitors and benzoylacrylamide derivatives Mitsubishi Chemical Corporation (JP) 1994-08-03 EP claimed
JP-6279272-A None JP disclosed
US-20250332286-A1 CHEMICALLY-MODIFIED ADENO-ASSOCIATED VIRUSES CENTRE NAT RECH SCIENT (FR) 2025-10-30 US disclosed
CN-119735523-A Food flavoring compound N-phenylacrylamide acid and preparation method and application thereof 华南理工大学 2025-04-01 CN disclosed
EP-4508222-A1 CHEMICALLY-MODIFIED ADENO-ASSOCIATED VIRUSES Centre National de la Recherche Scientifique (FR) 2025-02-19 EP disclosed
CN-117098815-A Rubberized asphalt composition having acrylic copolymer 巴斯夫欧洲公司 2023-11-21 CN disclosed
WO-2023198652-A1 CHEMICALLY-MODIFIED ADENO-ASSOCIATED VIRUSES CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (FR) 2023-10-19 WO disclosed
CN-114805127-B Preparation method of 2-trifluoromethyl-1-tetralone compound 武汉大学 2023-03-24 CN disclosed
CN-114805127-B Preparation method of 2-trifluoromethyl-1-tetralone compound 武汉大学 2023-03-24 CN disclosed
US-20020188084-A1 Stimuli-responsive polymer utilizing keto-enol tautomerization and stimuli-responsive separating material and chemical-releasing capsule comprising the same JNC CORPORATION (JP) 2002-12-12 US disclosed
EP-0922715-A2 Stimuli-responsive polymer utilizing keto-enol tautomerization AGENCY OF INDUSTRIAL SCIENCE AND TECHNOLOGY MITI (JP) 1999-06-16 EP disclosed
US-5618829-A SUPPRESSION GROWTH OF CANCER CELLS MITSUBISHI CHEMICAL CORPORATION (JP) 1997-04-08 US disclosed
US-5618829-A SUPPRESSION GROWTH OF CANCER CELLS MITSUBISHI CHEMICAL CORPORATION (JP) 1997-04-08 US disclosed
JP-H06279272-A TYROSINE KINASE INHIBITOR MITSUBISHI KASEI CORP 1994-10-04 JP disclosed
EP-0608897-A2 Tyrosine kinase inhibitors and benzoylacrylamide derivatives Mitsubishi Chemical Corporation (JP) 1994-08-03 EP disclosed
EP-0608897-A2 Tyrosine kinase inhibitors and benzoylacrylamide derivatives Mitsubishi Chemical Corporation (JP) 1994-08-03 EP disclosed
EP-0608897-A2 Tyrosine kinase inhibitors and benzoylacrylamide derivatives Mitsubishi Chemical Corporation (JP) 1994-08-03 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250332286-A1 CHEMICALLY-MODIFIED ADENO-ASSOCIATED VIRUSES AMDHD2, AADAC, ALDH1A2 AKT1 4706/4885TGM2 2212/4885ALDH1A1 9/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.