Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.51 |
| ▸ | MAPT | P10636 | 3/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.51 |
| ▸ | RAB9A | P51151 | 3/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.49 |
| ▸ | NPC1 | O15118 | 2/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 2/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | P2RY12 | Q9H244 | 2/20 | 0.46 |
| ▸ | CETP | P11597 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL10405355 | 0.99 | ALDH1A1 (0.50) | ALDH1A1MAPTMAPK1RAB9ASMN1; SMN2 | |
| SCHEMBL10401568 | 0.84 | ALDH1A1 (0.67) | ALDH1A1MAPTMAPK1SMN1; SMN2KDM4E | |
| SCHEMBL10401922 | 0.84 | MAPT (0.51) | ALDH1A1MAPTRAB9ASMN1; SMN2NPC1 | |
| SCHEMBL10401393 | 0.83 | ALDH1A1 (0.54) | ALDH1A1MAPTMAPK1SMN1; SMN2NPC1 | |
| SCHEMBL10401407 | 0.83 | ALDH1A1 (0.54) | ALDH1A1MAPTMAPK1SMN1; SMN2KDM4E | |
| Hydrochloric Acid SCHEMBL10401866 | 0.83 | ALDH1A1 (0.66) | ALDH1A1MAPTMAPK1SMN1; SMN2KDM4E | |
| SCHEMBL6134787 | 0.83 | ALDH1A1 (0.56) | ALDH1A1MAPTMAPK1RAB9ASMN1; SMN2 | |
| SCHEMBL10401408 | 0.82 | ALDH1A1 (0.53) | ALDH1A1MAPTMAPK1SMN1; SMN2NPC1 | |
| SCHEMBL10401976 | 0.81 | L3MBTL1 (0.59) | ALDH1A1MAPTMAPK1SMN1; SMN2NPC1 | |
| SCHEMBL10401434 | 0.81 | ALDH1A1 (0.50) | ALDH1A1MAPTMAPK1RAB9ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4960776-A | ANTIALLERGENS | A. H. ROBINS COMPANY, INC. (US) | 1990-10-02 | — | — | US | claimed |
| EP-0277725-A2 | 4-Aryl-N-[2-(dialkylamino and heterocyclicamino) alkyl]-1-piperazinecarboxamides and their use as anti allergy agents | A.H. ROBINS COMPANY, INCORPORATED (US) | 1988-08-10 | — | — | EP | claimed |
| US-4960776-A | ANTIALLERGENS | A. H. ROBINS COMPANY, INC. (US) | 1990-10-02 | — | — | US | disclosed |