Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM4 | P08173 | 1/20 | 0.55 |
| ▸ | LMNA | P02545 | 2/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.53 |
| ▸ | MAPT | P10636 | 1/20 | 0.53 |
| ▸ | HTT | P42858 | 1/20 | 0.53 |
| ▸ | PANK3 | Q9H999 | 1/20 | 0.53 |
| ▸ | HTR1A | P08908 | 2/20 | 0.52 |
| ▸ | HTR2A | P28223 | 2/20 | 0.52 |
| ▸ | HTR7 | P34969 | 2/20 | 0.52 |
| ▸ | HTR6 | P50406 | 2/20 | 0.52 |
| ▸ | CA12 | O43570 | 1/20 | 0.51 |
| ▸ | CA1 | P00915 | 1/20 | 0.51 |
| ▸ | CA9 | Q16790 | 1/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.51 |
| ▸ | TSHR | P16473 | 1/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.51 |
| ▸ | RECQL | P46063 | 1/20 | 0.51 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Oxalic Acid SCHEMBL10401881 | 0.96 | CHRM4 (0.54) | CHRM4LMNAALDH1A1SMN1; SMN2MAPT | |
| SCHEMBL10401770 | 0.88 | CHRM4 (0.57) | CHRM4LMNAALDH1A1SMN1; SMN2MAPT | |
| SCHEMBL10401771 | 0.87 | DRD2 (0.60) | LMNASMN1; SMN2MAPTHTTCA12 | |
| Oxalic Acid SCHEMBL10401914 | 0.86 | MEN1 (0.60) | LMNAALDH1A1SMN1; SMN2MAPTHTT | |
| Oxalic Acid SCHEMBL10402175 | 0.84 | DRD2 (0.57) | LMNASMN1; SMN2MAPTHTTCA12 | |
| Oxalic Acid SCHEMBL10402150 | 0.83 | DRD2 (0.56) | SMN1; SMN2MAPTHTTCA12CA1 | |
| Maleic Acid SCHEMBL10401426 | 0.82 | RAB9A (0.61) | CHRM4LMNAALDH1A1SMN1; SMN2MAPT | |
| Fumaric Acid SCHEMBL10401427 | 0.82 | RAB9A (0.61) | CHRM4LMNAALDH1A1SMN1; SMN2MAPT | |
| SCHEMBL10401381 | 0.80 | TP53 (0.57) | CHRM4LMNAALDH1A1SMN1; SMN2MAPT | |
| SCHEMBL11051123 | 0.76 | HTR1A (0.61) | LMNAALDH1A1SMN1; SMN2MAPTHTR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4960776-A | ANTIALLERGENS | A. H. ROBINS COMPANY, INC. (US) | 1990-10-02 | — | — | US | claimed |
| EP-0277725-A2 | 4-Aryl-N-[2-(dialkylamino and heterocyclicamino) alkyl]-1-piperazinecarboxamides and their use as anti allergy agents | A.H. ROBINS COMPANY, INCORPORATED (US) | 1988-08-10 | — | — | EP | claimed |