Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KIF11 | P52732 | 1/20 | 0.36 |
| ▸ | BACE1 | P56817 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5887218 | 0.80 | LTA4H (0.46) | BACE1ALDH1A1 | |
| Ethane SCHEMBL27743200 | 0.72 | PDE4B (0.32) | — | |
| SCHEMBL6505018 | 0.69 | PDE4B (0.40) | BACE1ALDH1A1TSHR | |
| SCHEMBL31497105 | 0.67 | ALDH1A1 (0.47) | BACE1ALDH1A1 | |
| SCHEMBL8005753 | 0.67 | KIF11 (0.36) | KIF11BACE1ALDH1A1TSHR | |
| Ethane SCHEMBL27811114 | 0.64 | — | — | |
| SCHEMBL8014938 | 0.63 | KIF11 (0.36) | KIF11BACE1ALDH1A1TSHR | |
| SCHEMBL14723151 | 0.63 | BACE1 (0.34) | BACE1ALDH1A1 | |
| Biphenyl SCHEMBL27543247 | 0.62 | ALDH1A1 (0.64) | KIF11BACE1ALDH1A1TSHR | |
| SCHEMBL9506721 | 0.61 | KMT2A (0.42) | BACE1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4894368-A | CARDIOVASCULAR DISORDERS, DIURETICS | AMERICAN CYANAMID COMPANY (US) | 1990-01-16 | — | — | US | disclosed |