Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKR1B1 | P15121 | 4/20 | 0.42 |
| ▸ | GHSR | Q92847 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10401769 | 0.83 | AKR1B1 (0.52) | AKR1B1GHSR | |
| SCHEMBL10401578 | 0.83 | AKR1B1 (0.62) | AKR1B1 | |
| SCHEMBL10401325 | 0.80 | AKR1B1 (0.38) | AKR1B1 | |
| SCHEMBL10401637 | 0.67 | DDB1 (0.35) | AKR1B1 | |
| SCHEMBL9525319 | 0.63 | ALDH1A1 (0.47) | — | |
| SCHEMBL9383374 | 0.62 | AKR1B1 (0.81) | AKR1B1 | |
| SCHEMBL8804611 | 0.59 | AKR1B1 (1.00) | AKR1B1 | |
| SCHEMBL11073412 | 0.58 | PDE7A (0.33) | AKR1B1 | |
| SCHEMBL11375295 | 0.58 | SLC6A2 (0.38) | — | |
| SCHEMBL11070635 | 0.57 | KDM1A (0.36) | AKR1B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4946858-A | ANTIDIABETIC AGENTS | AMERICAN HOME PRODUCTS CORPORATION (US) | 1990-08-07 | — | — | US | claimed |
| US-4946858-A | ANTIDIABETIC AGENTS | AMERICAN HOME PRODUCTS CORPORATION (US) | 1990-08-07 | — | — | US | disclosed |
| US-4900739-A | ANTIDIABETIC AGENTS | AMERICAN HOME PRODUCTS CORP. (US) | 1990-02-13 | — | — | US | disclosed |