Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.32 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.32 |
| ▸ | KDR | P35968 | 1/20 | 0.31 |
| ▸ | SOS1 | Q07889 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9647144 | 0.87 | PTPN1 (0.38) | KDM4EALDH1A1 | |
| SCHEMBL10401598 | 0.80 | NR4A2 (0.34) | MAPTGAAKDM4ENR4A2ALDH1A1 | |
| Bromide SCHEMBL10402341 | 0.79 | NR4A2 (0.33) | MAPTGAAKDM4ENR4A2ALDH1A1 | |
| Hydrochloric Acid SCHEMBL10401912 | 0.71 | ALDH1A1 (0.32) | GAAALDH1A1 | |
| SCHEMBL10401974 | 0.71 | ALDH1A1 (0.39) | KMT2AMAPTKDM4ENR4A2ALDH1A1 | |
| SCHEMBL17201278 | 0.70 | SOS1 (0.42) | KMT2AMAPTMEN1GAAKDM4E | |
| SCHEMBL9648247 | 0.68 | ALDH1A1 (0.37) | KMT2AMAPTKDM4EALDH1A1 | |
| SCHEMBL17201262 | 0.67 | SOS1 (0.39) | KMT2AMAPTMEN1GAAKDM4E | |
| SCHEMBL17201322 | 0.67 | SOS1 (0.49) | KMT2AMAPTMEN1GAAKDM4E | |
| SCHEMBL27185644 | 0.67 | SOS1 (0.49) | KMT2AMAPTMEN1GAAKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4923865-A | Substituted 1-(1H-imidazol-4-yl)alkyl-benzamides as anti-ischemics and as alpha-2-adrenergic receptor agonists | U C B SOCIETE ANONYME (BE) | 1990-05-08 | — | — | US | disclosed |