Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.37 |
| ▸ | HMGB1 | P09429 | 1/20 | 0.35 |
| ▸ | CXCL12 | P48061 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.35 |
| ▸ | SELL | P14151 | 1/20 | 0.33 |
| ▸ | SELP | P16109 | 1/20 | 0.33 |
| ▸ | GRM1 | Q13255 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | GLO1 | Q04760 | 1/20 | 0.30 |
| ▸ | ME2 | P23368 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9645373 | 0.88 | NNMT (0.32) | TDP1 | |
| SCHEMBL10401598 | 0.86 | NR4A2 (0.34) | ALDH1A1KDM4EHPGDHSD17B10MAPT | |
| Bromide SCHEMBL10402341 | 0.85 | NR4A2 (0.33) | ALDH1A1KDM4EHPGDHSD17B10MAPT | |
| SCHEMBL9647525 | 0.76 | P2RX3 (0.34) | NOTUMMAPTCYP3A4CYP2C9ME2 | |
| SCHEMBL9518487 | 0.75 | HMGB1 (0.48) | ALDH1A1KDM4EHPGDHSD17B10HMGB1 | |
| Hydrochloric Acid SCHEMBL10401999 | 0.74 | HMGB1 (0.47) | ALDH1A1KDM4EHPGDHSD17B10HMGB1 | |
| SCHEMBL2103783 | 0.73 | TAAR1 (0.46) | ALDH1A1HSD17B10POLBMAPTCYP3A4 | |
| SCHEMBL17941538 | 0.72 | ALDH1A1 (0.49) | ALDH1A1KDM4EHPGDHSD17B10HMGB1 | |
| SCHEMBL2581660 | 0.71 | KDM4E (0.50) | ALDH1A1KDM4EHPGDHSD17B10HMGB1 | |
| SCHEMBL11050063 | 0.70 | NOS2 (0.34) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0341231-B1 | SUBSTITUTED 1-(1H-IMIDAZOL-4-YL)ALKYL BENZAMIDES | U C B, S.A. (BE) | 1992-11-19 | — | — | EP | disclosed |
| EP-0341231-A1 | Substituted 1-(1H-imidazol-4-yl)alkyl benzamides | U C B, S.A. (BE) | 1989-11-08 | — | — | EP | disclosed |