Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR4A2 | P43354 | 4/20 | 0.34 |
| ▸ | MAP2K1 | Q02750 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | MITF | O75030 | 1/20 | 0.33 |
| ▸ | CA12 | O43570 | 1/20 | 0.33 |
| ▸ | CA1 | P00915 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
| ▸ | CA7 | P43166 | 1/20 | 0.33 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.33 |
| ▸ | PDK4 | Q16654 | 1/20 | 0.33 |
| ▸ | CA9 | Q16790 | 1/20 | 0.33 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.33 |
| ▸ | RNASEH1 | O60930 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 3/20 | 0.32 |
| ▸ | GLA | P06280 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 2/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | HPGD | P15428 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Bromide SCHEMBL10402341 | 0.99 | NR4A2 (0.33) | NR4A2MAP2K1KDM4EMAPTMITF | |
| SCHEMBL9648247 | 0.86 | ALDH1A1 (0.37) | KDM4EMAPTALDH1A1HPGDHSD17B10 | |
| SCHEMBL9645373 | 0.85 | NNMT (0.32) | — | |
| SCHEMBL10401641 | 0.80 | KMT2A (0.34) | NR4A2KDM4EMAPTGAAALDH1A1 | |
| SCHEMBL10401974 | 0.79 | ALDH1A1 (0.39) | NR4A2MAP2K1KDM4EMAPTTSHR | |
| SCHEMBL25038962 | 0.72 | ALDH1A1 (0.51) | MAP2K1KDM4EMAPTGAAGLA | |
| SCHEMBL20558617 | 0.71 | CA12 (0.41) | KDM4EMAPTMITFCA12CA1 | |
| SCHEMBL8321013 | 0.71 | CTSD (0.41) | MAPTMITFCA12CA1CA2 | |
| SCHEMBL10401616 | 0.71 | CA12 (0.41) | KDM4EMAPTCA12CA1CA2 | |
| SCHEMBL10401901 | 0.70 | ALDH1A1 (0.38) | NR4A2MAP2K1KDM4EMAPTGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4923865-A | Substituted 1-(1H-imidazol-4-yl)alkyl-benzamides as anti-ischemics and as alpha-2-adrenergic receptor agonists | U C B SOCIETE ANONYME (BE) | 1990-05-08 | — | — | US | disclosed |