Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | HTT | P42858 | 2/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | MITF | O75030 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | GFER | P55789 | 1/20 | 0.40 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.40 |
| ▸ | ATM | Q13315 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.38 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.37 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10403564 | 0.84 | CHRNA7 (0.40) | ALDH1A1HTTMITFRAB9AGFER | |
| SCHEMBL10403268 | 0.74 | ALDH1A1 (0.40) | ALDH1A1HTTMITFRAB9AGFER | |
| SCHEMBL23964577 | 0.73 | SMN1; SMN2 (0.38) | ALDH1A1HTTHSD17B10RAB9APAX8 | |
| SCHEMBL809550 | 0.72 | ALDH1A1 (0.41) | ALDH1A1HTTHSD17B10PAX8SMN1; SMN2 | |
| SCHEMBL10403562 | 0.71 | CHRNA7 (0.40) | ALDH1A1HTTMITFRAB9AGFER | |
| SCHEMBL1894871 | 0.70 | EPHX1 (0.44) | SIGMAR1MEN1KMT2A | |
| SCHEMBL809553 | 0.67 | PPARG (0.43) | PAX8SMN1; SMN2TSHR | |
| SCHEMBL11534852 | 0.67 | ALDH1A1 (0.47) | ALDH1A1HTTHSD17B10RAB9AATM | |
| SCHEMBL11594651 | 0.66 | KDM4E (0.45) | ALDH1A1KDM4ECYP2D6TSHRHIF1A | |
| SCHEMBL809514 | 0.66 | LMNA (0.41) | ALDH1A1PAX8SMN1; SMN2SIGMAR1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4914206-A | ANTIBIOTICS | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1990-04-03 | — | — | US | disclosed |
| EP-0226896-A2 | Lankacidin derivatives and production thereof | Takeda Chemical Industries, Ltd. (JP) | 1987-07-01 | — | — | EP | disclosed |