Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRNA7 | P36544 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | MITF | O75030 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | GFER | P55789 | 1/20 | 0.37 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.37 |
| ▸ | ATM | Q13315 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.36 |
| ▸ | LTA4H | P09960 | 2/20 | 0.35 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.35 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.35 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10403269 | 0.84 | ALDH1A1 (0.40) | CHRNA7KDM4ECYP2D6TSHRHIF1A | |
| SCHEMBL10403562 | 0.74 | CHRNA7 (0.40) | CHRNA7KDM4ECYP2D6TSHRHIF1A | |
| SCHEMBL10403268 | 0.71 | ALDH1A1 (0.40) | CHRNA7KDM4ECYP2D6TSHRHIF1A | |
| SCHEMBL11534852 | 0.67 | ALDH1A1 (0.47) | TSHRHIF1AALDH1A1HTTRAB9A | |
| SCHEMBL11594651 | 0.66 | KDM4E (0.45) | KDM4ECYP2D6TSHRHIF1AALDH1A1 | |
| SCHEMBL17810249 | 0.65 | ALDH1A1 (0.55) | KDM4ECYP2D6TSHRHIF1AALDH1A1 | |
| SCHEMBL9130301 | 0.65 | ALDH1A1 (0.50) | KDM4ECYP2D6TSHRHIF1AALDH1A1 | |
| SCHEMBL3920722 | 0.64 | ALDH1A1 (0.51) | CHRNA7KDM4EALDH1A1HTTRAB9A | |
| SCHEMBL30101423 | 0.64 | ALDH1A1 (0.53) | KDM4ECYP2D6TSHRHIF1AALDH1A1 | |
| Hydrochloric Acid SCHEMBL11591663 | 0.64 | MAPT (0.58) | KDM4ECYP2D6TSHRHIF1AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4914206-A | ANTIBIOTICS | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1990-04-03 | — | — | US | disclosed |
| EP-0226896-A2 | Lankacidin derivatives and production thereof | Takeda Chemical Industries, Ltd. (JP) | 1987-07-01 | — | — | EP | disclosed |