Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 5/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | CA1 | P00915 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
| ▸ | CA4 | P22748 | 1/20 | 0.33 |
| ▸ | CA7 | P43166 | 1/20 | 0.33 |
| ▸ | CA9 | Q16790 | 1/20 | 0.33 |
| ▸ | P2RY12 | Q9H244 | 1/20 | 0.33 |
| ▸ | VDR | P11473 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | DNMT1 | P26358 | 1/20 | 0.32 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10402284 | 0.89 | KMT2A (0.37) | KMT2ANPC1LMNAHTTSMN1; SMN2 | |
| SCHEMBL10403646 | 0.81 | KMT2A (0.39) | KMT2ANPC1LMNAHTTSMN1; SMN2 | |
| SCHEMBL10404243 | 0.81 | ALDH1A1 (0.49) | KMT2ANPC1LMNAHTTSMN1; SMN2 | |
| SCHEMBL10402285 | 0.79 | KMT2A (0.37) | KMT2ANPC1LMNAHTTSMN1; SMN2 | |
| SCHEMBL10405293 | 0.72 | KMT2A (0.39) | KMT2ALMNAHTTALDH1A1MAPT | |
| SCHEMBL10403886 | 0.72 | DCUN1D1 (0.40) | NPC1LMNAHTTALDH1A1MAPT | |
| SCHEMBL10402083 | 0.70 | ALDH1A1 (0.30) | LMNAALDH1A1KDM4E | |
| SCHEMBL10403232 | 0.70 | USP2 (0.36) | KMT2ALMNAHTTALDH1A1HSD17B10 | |
| SCHEMBL10402249 | 0.70 | ALDH1A1 (0.48) | KMT2ANPC1LMNASMN1; SMN2ALDH1A1 | |
| SCHEMBL7141187 | 0.69 | KMT2A (0.44) | KMT2ANPC1LMNAHTTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4914206-A | ANTIBIOTICS | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1990-04-03 | — | — | US | disclosed |
| EP-0226896-A2 | Lankacidin derivatives and production thereof | Takeda Chemical Industries, Ltd. (JP) | 1987-07-01 | — | — | EP | disclosed |