Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP2 | O75604 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 3/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
| ▸ | MTNR1A | P48039 | 3/20 | 0.34 |
| ▸ | MTNR1B | P49286 | 3/20 | 0.34 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.33 |
| ▸ | GRM2 | Q14416 | 2/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.32 |
| ▸ | IMPDH2 | P12268 | 1/20 | 0.32 |
| ▸ | IMPDH1 | P20839 | 1/20 | 0.32 |
| ▸ | MIF | P14174 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10402218 | 0.88 | USP2 (0.36) | USP2MAPK1LMNAALDH1A1PKM | |
| SCHEMBL10404331 | 0.85 | MTNR1A (0.49) | USP2MAPK1ALDH1A1MTNR1AMTNR1B | |
| SCHEMBL10403024 | 0.78 | USP2 (0.37) | USP2MAPK1LMNAALDH1A1PKM | |
| SCHEMBL10767204 | 0.77 | LMNA (0.48) | LMNAALDH1A1PKMHSD17B10KMT2A | |
| SCHEMBL10402220 | 0.75 | USP2 (0.38) | USP2MAPK1LMNAALDH1A1PKM | |
| SCHEMBL10403605 | 0.70 | L3MBTL1 (0.43) | LMNAALDH1A1PKMCYP19A1HTT | |
| SCHEMBL10402083 | 0.68 | ALDH1A1 (0.30) | LMNAALDH1A1PKM | |
| SCHEMBL10404178 | 0.67 | TSHR (0.33) | — | |
| SCHEMBL10403022 | 0.67 | CYP19A1 (0.41) | USP2MAPK1LMNAALDH1A1CYP19A1 | |
| SCHEMBL13113137 | 0.67 | PKM (0.51) | LMNAALDH1A1PKMHTTHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4914206-A | ANTIBIOTICS | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1990-04-03 | — | — | US | disclosed |
| EP-0226896-A2 | Lankacidin derivatives and production thereof | Takeda Chemical Industries, Ltd. (JP) | 1987-07-01 | — | — | EP | disclosed |