Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 10/20 | 0.49 |
| ▸ | LMNA | P02545 | 4/20 | 0.49 |
| ▸ | RAB9A | P51151 | 4/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.44 |
| ▸ | NPC1 | O15118 | 3/20 | 0.44 |
| ▸ | HPGD | P15428 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.39 |
| ▸ | MAPT | P10636 | 3/20 | 0.39 |
| ▸ | MEN1 | O00255 | 3/20 | 0.39 |
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | PKM | P14618 | 2/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | VDR | P11473 | 1/20 | 0.36 |
| ▸ | USP2 | O75604 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10402249 | 0.89 | ALDH1A1 (0.48) | ALDH1A1LMNARAB9ASMN1; SMN2NPC1 | |
| SCHEMBL10404244 | 0.82 | ALDH1A1 (0.50) | ALDH1A1LMNARAB9ASMN1; SMN2NPC1 | |
| SCHEMBL10403645 | 0.81 | KMT2A (0.38) | ALDH1A1LMNASMN1; SMN2NPC1KDM4E | |
| SCHEMBL10402251 | 0.80 | ALDH1A1 (0.48) | ALDH1A1LMNARAB9ASMN1; SMN2NPC1 | |
| SCHEMBL10403758 | 0.76 | ALDH1A1 (0.58) | ALDH1A1LMNARAB9ASMN1; SMN2NPC1 | |
| SCHEMBL7140573 | 0.72 | ALDH1A1 (0.49) | ALDH1A1LMNARAB9ASMN1; SMN2NPC1 | |
| SCHEMBL10767204 | 0.72 | LMNA (0.48) | ALDH1A1LMNARAB9ASMN1; SMN2NPC1 | |
| SCHEMBL10767199 | 0.72 | ALDH1A1 (0.52) | ALDH1A1LMNARAB9ASMN1; SMN2NPC1 | |
| SCHEMBL10404254 | 0.71 | ALDH1A1 (0.58) | ALDH1A1LMNARAB9ASMN1; SMN2NPC1 | |
| SCHEMBL10402503 | 0.71 | KMT2A (0.43) | ALDH1A1LMNARAB9ASMN1; SMN2NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4914206-A | ANTIBIOTICS | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1990-04-03 | — | — | US | disclosed |
| EP-0226896-A2 | Lankacidin derivatives and production thereof | Takeda Chemical Industries, Ltd. (JP) | 1987-07-01 | — | — | EP | disclosed |