Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.33 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.31 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.31 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.31 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10402061 | 0.85 | TSHR (0.33) | TSHRCHRM2CHRM4CHRM1TBXA2R | |
| SCHEMBL6384348 | 0.77 | — | — | |
| SCHEMBL6379373 | 0.74 | TSHR (0.37) | TSHRCHRM2CHRM4CHRM1TBXA2R | |
| SCHEMBL6384305 | 0.72 | ALDH1A1 (0.40) | TSHR | |
| SCHEMBL6382808 | 0.71 | GPR84 (0.44) | — | |
| SCHEMBL4952696 | 0.71 | TSHR (0.34) | TSHRCHRM2CHRM4CHRM1TBXA2R | |
| SCHEMBL10525917 | 0.69 | TDP1 (0.48) | TSHRCHRM2CHRM4CHRM1TBXA2R | |
| SCHEMBL10404331 | 0.69 | MTNR1A (0.49) | TSHR | |
| SCHEMBL10404182 | 0.69 | TSHR (0.33) | TSHRCHRM2CHRM4CHRM1TBXA2R | |
| SCHEMBL7575626 | 0.69 | TSHR (0.32) | TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4914206-A | ANTIBIOTICS | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1990-04-03 | — | — | US | disclosed |
| EP-0226896-A2 | Lankacidin derivatives and production thereof | Takeda Chemical Industries, Ltd. (JP) | 1987-07-01 | — | — | EP | disclosed |