Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1A | P48039 | 7/20 | 0.49 |
| ▸ | MTNR1B | P49286 | 7/20 | 0.49 |
| ▸ | MAOA | P21397 | 1/20 | 0.42 |
| ▸ | MAOB | P27338 | 1/20 | 0.42 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | FKBP1A | P62942 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 2/20 | 0.36 |
| ▸ | RAB9A | P51151 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | CASP1 | P29466 | 1/20 | 0.36 |
| ▸ | CASP7 | P55210 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10767204 | 0.80 | LMNA (0.48) | MEN1KMT2AHSD17B10TSHRALDH1A1 | |
| SCHEMBL10404334 | 0.76 | MTNR1A (0.50) | MTNR1AMTNR1BMAOAMAOBFFAR1 | |
| SCHEMBL9665783 | 0.76 | ALDH1A1 (0.46) | MTNR1AMTNR1BMEN1KMT2AHSD17B10 | |
| SCHEMBL10402218 | 0.73 | USP2 (0.36) | MTNR1AMTNR1BKMT2AHSD17B10HTT | |
| SCHEMBL23259386 | 0.70 | MTNR1A (0.50) | MTNR1AMTNR1BMAOAMAOBFFAR1 | |
| SCHEMBL9009563 | 0.70 | MTNR1A (0.49) | MTNR1AMTNR1BMAOAMAOBFFAR1 | |
| SCHEMBL10404178 | 0.69 | TSHR (0.33) | TSHR | |
| SCHEMBL914115 | 0.69 | MTNR1A (0.49) | MTNR1AMTNR1BMAOAMAOBFFAR1 | |
| SCHEMBL13659834 | 0.68 | MAOA (0.58) | MTNR1AMTNR1BMAOAMAOBFFAR1 | |
| SCHEMBL3175997 | 0.68 | MTNR1A (0.51) | MTNR1AMTNR1BMAOAMAOBFFAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4914206-A | ANTIBIOTICS | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1990-04-03 | — | — | US | disclosed |
| EP-0226896-A2 | Lankacidin derivatives and production thereof | Takeda Chemical Industries, Ltd. (JP) | 1987-07-01 | — | — | EP | disclosed |