Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MIF | P14174 | 2/20 | 0.38 |
| ▸ | MAOA | P21397 | 1/20 | 0.38 |
| ▸ | MAOB | P27338 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | MGLL | Q99685 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.33 |
| ▸ | GAA | P10253 | 2/20 | 0.33 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10403862 | 0.78 | MEN1 (0.41) | MIFSMN1; SMN2LMNAALDH1A1POLB | |
| SCHEMBL949801 | 0.77 | LMNA (0.39) | MAOAMAOBSMN1; SMN2MAPTHPGD | |
| SCHEMBL9427770 | 0.73 | MAOA (0.41) | MAOAMAOBSMN1; SMN2MAPTHPGD | |
| SCHEMBL15141725 | 0.72 | APP (0.42) | MAOAMAOBSMN1; SMN2MAPTHPGD | |
| SCHEMBL5173197 | 0.72 | SMN1; SMN2 (0.45) | MAOAMAOBSMN1; SMN2MAPTHPGD | |
| SCHEMBL343269 | 0.72 | SMN1; SMN2 (0.45) | MAOAMAOBSMN1; SMN2MAPTHPGD | |
| SCHEMBL1453001 | 0.72 | SMN1; SMN2 (0.45) | MAOAMAOBSMN1; SMN2MAPTHPGD | |
| SCHEMBL1713865 | 0.72 | SMN1; SMN2 (0.50) | MAOAMAOBSMN1; SMN2MAPTHPGD | |
| SCHEMBL16586148 | 0.71 | MAOA (0.40) | MAOAMAOBSMN1; SMN2MAPTHPGD | |
| Fluoride SCHEMBL1336886 | 0.70 | MAOA (0.48) | MAOAMAOBSMN1; SMN2MAPTHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4914206-A | ANTIBIOTICS | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1990-04-03 | — | — | US | disclosed |
| EP-0226896-A2 | Lankacidin derivatives and production thereof | Takeda Chemical Industries, Ltd. (JP) | 1987-07-01 | — | — | EP | disclosed |