Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.49 |
| ▸ | LMNA | P02545 | 3/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.43 |
| ▸ | NPC1 | O15118 | 2/20 | 0.43 |
| ▸ | RAB9A | P51151 | 2/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.43 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.41 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.41 |
| ▸ | VDR | P11473 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | HTT | P42858 | 2/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | EHMT2 | Q96KQ7 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7140571 | 0.80 | EHMT2 (0.40) | ALDH1A1LMNAKDM4ESMN1; SMN2NPC1 | |
| SCHEMBL28588859 | 0.77 | EHMT2 (0.47) | ALDH1A1LMNAKDM4ESMN1; SMN2NPC1 | |
| SCHEMBL7133969 | 0.77 | EHMT2 (0.47) | ALDH1A1LMNAKDM4ESMN1; SMN2NPC1 | |
| SCHEMBL10330811 | 0.76 | DNMT1 (0.53) | ALDH1A1LMNAKDM4ESMN1; SMN2NPC1 | |
| SCHEMBL25376470 | 0.73 | ALDH1A1 (0.47) | ALDH1A1LMNAKDM4ESMN1; SMN2NPC1 | |
| SCHEMBL10404244 | 0.73 | ALDH1A1 (0.50) | ALDH1A1LMNAKDM4ESMN1; SMN2NPC1 | |
| SCHEMBL23241350 | 0.73 | DNMT1 (0.52) | ALDH1A1LMNASMN1; SMN2RAB9AKEAP1 | |
| SCHEMBL3100559 | 0.73 | KEAP1 (0.51) | ALDH1A1LMNAKDM4ESMN1; SMN2HPGD | |
| SCHEMBL7141187 | 0.73 | KMT2A (0.44) | ALDH1A1LMNAKDM4ESMN1; SMN2NPC1 | |
| SCHEMBL10404243 | 0.72 | ALDH1A1 (0.49) | ALDH1A1LMNAKDM4ESMN1; SMN2NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1086124-B1 | NOVEL CYCLOSPORINS | CHEM AG C (CH) | 2003-11-19 | — | — | EP | disclosed |
| US-6583265-B1 | Compound for use in the prevention of viral and bacterial infections | C-CHEM AG (CH) | 2003-06-24 | — | — | US | disclosed |