⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11050912 | 0.73 | — | — | |
| SCHEMBL11311736 | 0.73 | CYP2E1 (0.41) | — | |
| SCHEMBL5546776 | 0.72 | ALDH1A1 (0.38) | — | |
| SCHEMBL8671567 | 0.72 | MMP8 (0.46) | — | |
| SCHEMBL190205 | 0.70 | — | — | |
| SCHEMBL256014 | 0.69 | — | — | |
| SCHEMBL1372325 | 0.69 | — | — | |
| SCHEMBL7012372 | 0.69 | — | — | |
| SCHEMBL8626062 | 0.68 | MEN1 (0.36) | — | |
| Hydrochloric Acid SCHEMBL719171 | 0.67 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 71 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4388310-A | ANTIBIOTIC | MERCK & CO., INC. (US) | 1983-06-14 | — | — | US | claimed |
| US-4298741-A | DETHIAPENICILLIN ANTIBIOTICS | MERCK & CO., INC. (US) | 1981-11-03 | — | — | US | claimed |
| US-4281002-A | ANTIBIOTICS | MERCK & CO., INC. (US) | 1981-07-28 | — | — | US | claimed |
| US-4277482-A | AMINO ACID DERIVATIVE ANTIBIOTICS | MERCK & CO., INC. (US) | 1981-07-07 | — | — | US | claimed |
| US-4255423-A | BACTERICIDES | MERCK & CO., INC. (US) | 1981-03-10 | — | — | US | claimed |
| US-4215124-A | ANTIBIOTICS | MERCK & CO., INC. (US) | 1980-07-29 | — | — | US | claimed |
| EP-0002210-A1 | 6- and 6,6- disubstituted-2-substituted-pen-2-em-3-carboxylic acids; processes for their preparation and pharmaceutical compositions containing such compounds | MERCK & CO. INC. (US) | 1979-06-13 | — | — | EP | claimed |
| US-4086423-A | CEPHALOSPORINS, CYCLOADDITION OF GLYCINE DERIVATIVE TO THIAZINE COMPOUND | MERCK & CO., INC. (US) | 1978-04-25 | — | — | US | claimed |
| CN-115557928-B | Synthesis method of 2-chlorothiophene-5-formic acid | 浙江燎原药业有限公司 | 2024-03-19 | — | — | CN | disclosed |
| CN-115557928-A | Synthetic method of 2-chlorothiophene-5-formic acid | 浙江燎原药业股份有限公司 | 2023-01-03 | — | — | CN | disclosed |
| US-4957912-A | ANTIBIOTICS | MERCK & CO., INC. (US) | 1990-09-18 | — | — | US | disclosed |
| US-4891370-A | ELASTASE INHIBITORS | MERCK & CO., INC. (US) | 1990-01-02 | — | — | US | disclosed |
| US-4839352-A | ANTIBIOTICS | MERCK & CO., INC. (US) | 1989-06-13 | — | — | US | disclosed |
| EP-0134301-A1 | 6-(1'-Hydroxyethyl)-3-substituted amino-1-azabicyclo(3.2.0)-hept-2-en-7-one-2-carboxylic acid | MERCK & CO. INC. (US) | 1985-03-20 | — | — | EP | disclosed |
| US-4053286-A | ACYLATION | MERCK & CO., INC. (US) | 1977-10-11 | — | — | US | disclosed |
| US-4032521-A | ANTIBIOTICS | MERCK & CO., INC. (US) | 1977-06-28 | — | — | US | disclosed |
| US-4014873-A | Process for the production of 7-acylamidocephalosporins | MERCK & CO., INC. (US) | 1977-03-29 | — | — | US | disclosed |
| US-3979384-A | ANTIBIOTICS | MERCK & CO., INC. (US) | 1976-09-07 | — | — | US | disclosed |
| US-3974151-A | Cephalosporin compounds | MERCK & CO., INC. (US) | 1976-08-10 | — | — | US | disclosed |
| US-3962231-A | ANTIBIOTICS | MERCK & CO., INC. (US) | 1976-06-08 | — | — | US | disclosed |