Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.40 |
| ▸ | PARP1 | P09874 | 7/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | GAA | P10253 | 2/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | CA1 | P00915 | 1/20 | 0.36 |
| ▸ | CA2 | P00918 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | ESRRG | P62508 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20037449 | 0.73 | KDM4E (0.53) | MAPTSMN1; SMN2ALDH1A1NPC1RAB9A | |
| SCHEMBL23657866 | 0.72 | RAB9A (0.54) | MAPTSMN1; SMN2ALDH1A1NPC1RAB9A | |
| SCHEMBL10405015 | 0.67 | L3MBTL1 (0.45) | MAPTSMN1; SMN2ALDH1A1GAARAB9A | |
| SCHEMBL20249206 | 0.66 | MTNR1A (0.46) | ESRRG | |
| SCHEMBL14430745 | 0.65 | KMT2A (0.53) | MAPTPARP1SMN1; SMN2ALDH1A1GAA | |
| SCHEMBL13545865 | 0.65 | TP53 (0.49) | MAPTSMN1; SMN2ALDH1A1NPC1RAB9A | |
| SCHEMBL16643809 | 0.64 | GAA (0.36) | SMN1; SMN2ALDH1A1GAANPC1RAB9A | |
| SCHEMBL17927741 | 0.64 | HCAR2 (0.39) | MAPTSMN1; SMN2ALDH1A1GAANPC1 | |
| SCHEMBL13545872 | 0.64 | MAPK1 (0.45) | MAPTPARP1SMN1; SMN2ALDH1A1GAA | |
| SCHEMBL15215450 | 0.63 | P4HTM (0.58) | ALDH1A1CA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4968805-A | Pyrazole derivatives and insecticidal fungicidal and miticidal compositions thereof | MITSUBISHI KASEI CORPORATION (JP) | 1990-11-06 | — | — | US | disclosed |