Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 9/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 8/20 | 0.53 |
| ▸ | NPC1 | O15118 | 7/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.53 |
| ▸ | LMNA | P02545 | 2/20 | 0.53 |
| ▸ | HTT | P42858 | 2/20 | 0.53 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.51 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.51 |
| ▸ | RELA | Q04206 | 1/20 | 0.51 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | ATM | Q13315 | 1/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10405014 | 0.72 | MAPT (0.40) | RAB9ASMN1; SMN2NPC1ALDH1A1MAPT | |
| SCHEMBL7783342 | 0.72 | EPHX1 (0.73) | RAB9ASMN1; SMN2NPC1ALDH1A1LMNA | |
| SCHEMBL14430745 | 0.71 | KMT2A (0.53) | SMN1; SMN2ALDH1A1LMNAALOX15TSHR | |
| SCHEMBL12717314 | 0.70 | SMN1; SMN2 (0.64) | RAB9ASMN1; SMN2NPC1ALDH1A1LMNA | |
| SCHEMBL8674157 | 0.70 | TAAR1 (0.61) | RAB9ASMN1; SMN2NPC1ALDH1A1LMNA | |
| SCHEMBL16629830 | 0.70 | BRD4 (0.42) | RAB9ASMN1; SMN2NPC1ALDH1A1TSHR | |
| SCHEMBL17927741 | 0.70 | HCAR2 (0.39) | RAB9ASMN1; SMN2NPC1ALDH1A1LMNA | |
| SCHEMBL6569873 | 0.69 | RAB9A (0.78) | RAB9ASMN1; SMN2NPC1ALDH1A1LMNA | |
| SCHEMBL15695713 | 0.68 | ALDH1A1 (0.67) | RAB9ASMN1; SMN2NPC1ALDH1A1LMNA | |
| SCHEMBL29650441 | 0.68 | RAB9A (0.70) | RAB9ASMN1; SMN2NPC1ALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210220408-A1 | ARYL HYDROCARBON RECEPTOR ANTAGONISTS AND METHODS OF USE | EDIGENE BIOTECHNOLOGY, INC. (CN) | 2021-07-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210220408-A1 | ARYL HYDROCARBON RECEPTOR ANTAGONISTS AND METHODS OF USE | AHR, ARNT, ARSA | RAB9A 4056/4885SMN1; SMN2 3198/4885NPC1 1022/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.