Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 11/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.55 |
| ▸ | TSHR | P16473 | 2/20 | 0.55 |
| ▸ | GLA | P06280 | 3/20 | 0.49 |
| ▸ | GAA | P10253 | 3/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.48 |
| ▸ | MAPT | P10636 | 2/20 | 0.48 |
| ▸ | KCNA3 | P22001 | 4/20 | 0.47 |
| ▸ | MCL1 | Q07820 | 2/20 | 0.46 |
| ▸ | POLB | P06746 | 5/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 5/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.45 |
| ▸ | APEX1 | P27695 | 1/20 | 0.45 |
| ▸ | RECQL | P46063 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | ATM | Q13315 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18788969 | 0.81 | KDM4E (0.54) | KDM4EALDH1A1TSHRGLAGAA | |
| SCHEMBL4185977 | 0.80 | KDM4E (0.68) | KDM4EALDH1A1TSHRMAPK1MAPT | |
| SCHEMBL11319802 | 0.78 | KDM4E (0.48) | KDM4EALDH1A1TSHRGLAGAA | |
| SCHEMBL10405189 | 0.77 | KDM4E (0.68) | KDM4EALDH1A1TSHRGLAGAA | |
| SCHEMBL11435078 | 0.75 | L3MBTL1 (0.57) | KDM4EALDH1A1TSHRGLAGAA | |
| SCHEMBL17174622 | 0.72 | KDM4E (0.47) | KDM4EALDH1A1TSHRGLAGAA | |
| SCHEMBL18155873 | 0.72 | KDM4E (0.67) | KDM4EALDH1A1TSHRGLAGAA | |
| SCHEMBL18788966 | 0.72 | KCNA3 (0.58) | KDM4EALDH1A1TSHRKCNA3KMT2A | |
| SCHEMBL18579074 | 0.71 | KDM4E (0.45) | KDM4EALDH1A1GLAGAAMAPK1 | |
| SCHEMBL10404718 | 0.71 | ALDH1A1 (1.00) | KDM4EALDH1A1TSHRGAAMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4950770-A | Psoralens aminomethylation | ELDER PHARMACEUTICALS, INC. (US) | 1990-08-21 | — | — | US | disclosed |
| US-4294822-A | 5-Aminoalkyl-4,4,8-trialkylpsoralens | THOMAS C. ELDER, INC. (US) | 1981-10-13 | — | — | US | disclosed |