Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DAO | P14920 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10402361 | 0.61 | PDE3B (0.37) | DAO | |
| SCHEMBL4265547 | 0.55 | ALDH1A1 (0.39) | DAO | |
| SCHEMBL9901221 | 0.54 | — | — | |
| SCHEMBL1362732 | 0.54 | GPR84 (0.53) | DAO | |
| SCHEMBL351958 | 0.52 | LMNA (0.38) | — | |
| SCHEMBL351471 | 0.52 | LMNA (0.38) | — | |
| SCHEMBL751507 | 0.52 | MEN1 (0.33) | — | |
| SCHEMBL6772531 | 0.52 | TSHR (0.33) | — | |
| SCHEMBL28818278 | 0.52 | GPR84 (0.51) | DAO | |
| SCHEMBL27891346 | 0.52 | CRBN (0.40) | DAO |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4952690-A | 6-substituted thia-aza compounds | CIBA-GEIGY CORPORATION (US) | 1990-08-28 | — | — | US | disclosed |
| US-4692442-A | ANTIBIOTICS | CIBA-GEIGY CORPORATION (US) | 1987-09-08 | — | — | US | disclosed |
| EP-0042026-B1 | 3,4-DISUBSTITUTED AZETIDIN-2-ON COMPOUNDS AND PROCESS FOR THEIR PREPARATION | CIBA-GEIGY AG (CH) | 1986-01-08 | — | — | EP | disclosed |
| US-4505894-A | ANTIBIOTICS, BATERICIDES | BEECHAM GROUP LIMITED (GB) | 1985-03-19 | — | — | US | disclosed |
| US-4428958-A | OXAPENICILLINS, BETA-LACTAMASE INHIBITORS | BEECHAM GROUP LIMITED (GB) | 1984-01-31 | — | — | US | disclosed |
| EP-0042026-A1 | 3,4-Disubstituted azetidin-2-on compounds and process for their preparation | CIBA-GEIGY AG (CH) | 1981-12-23 | — | — | EP | disclosed |
| EP-0009008-A2 | Cephalosporin derivatives, process for their preparation and pharmaceutical compositions containing them | CIBA-GEIGY AG (CH) | 1980-03-19 | — | — | EP | disclosed |
| EP-0003960-A1 | 6-Substituted thia-aza-compounds, their preparation and pharmaceutical compositions containing them | CIBA-GEIGY AG (CH) | 1979-09-19 | — | — | EP | disclosed |
| US-4024249-A | FOR COMBATTING MICROORGANISMS | CIBA-GEIGY CORPORATION (US) | 1977-05-17 | — | — | US | disclosed |
| US-4014874-A | Process for the manufacture of 3-substituted thiomethyl-7-amino-2-cephem-4-carboxylic acid compound | CIBA-GEIGY CORPORATION (US) | 1977-03-29 | — | — | US | disclosed |