Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1A | P08908 | 4/20 | 0.54 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.46 |
| ▸ | MTNR1A | P48039 | 6/20 | 0.46 |
| ▸ | MTNR1B | P49286 | 6/20 | 0.46 |
| ▸ | HTR2B | P41595 | 2/20 | 0.43 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.43 |
| ▸ | HTR7 | P34969 | 1/20 | 0.42 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.42 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.39 |
| ▸ | DRD2 | P14416 | 1/20 | 0.39 |
| ▸ | DRD3 | P35462 | 1/20 | 0.39 |
| ▸ | NQO2 | P16083 | 5/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9014302 | 0.92 | HTR1A (0.47) | HTR1AENPP2MTNR1AMTNR1BHTR2B | |
| SCHEMBL5479142 | 0.86 | HTR1A (0.54) | HTR1AENPP2MTNR1AMTNR1BHTR2B | |
| SCHEMBL5173384 | 0.80 | HTR1A (0.48) | HTR1AENPP2MTNR1AMTNR1BHTR2B | |
| SCHEMBL5175500 | 0.80 | HTR1A (0.56) | HTR1AENPP2MTNR1AMTNR1BHTR2B | |
| SCHEMBL5229125 | 0.80 | HTR1A (0.53) | HTR1AENPP2MTNR1AMTNR1BHTR2B | |
| SCHEMBL9669326 | 0.80 | HTR1A (0.58) | HTR1AENPP2MTNR1AMTNR1BHTR2B | |
| SCHEMBL5223857 | 0.79 | MTNR1A (0.72) | HTR1AMTNR1AMTNR1BNQO2 | |
| SCHEMBL10408558 | 0.78 | MAP3K14 (0.45) | HTR1AMTNR1AMTNR1BKCNH2DRD2 | |
| SCHEMBL10407837 | 0.78 | DRD3 (0.39) | HTR1AMTNR1AMTNR1BDRD2DRD3 | |
| SCHEMBL10407574 | 0.78 | ADRA2A (0.36) | HTR1AMTNR1AMTNR1BKCNH2DRD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4977166-A | ANTIARRHYTHMIC AND ANTIFIBRILLATORY AGENTS | RHONE-POULENC SANTE (FR) | 1990-12-11 | — | — | US | disclosed |