Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Terephthalic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 1/20 | 0.63 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.63 |
| ▸ | CA12 | O43570 | 1/20 | 0.61 |
| ▸ | CA1 | P00915 | 1/20 | 0.61 |
| ▸ | CA2 | P00918 | 1/20 | 0.61 |
| ▸ | CA3 | P07451 | 1/20 | 0.61 |
| ▸ | TYR | P14679 | 1/20 | 0.61 |
| ▸ | DRD1 | P21728 | 1/20 | 0.61 |
| ▸ | CA4 | P22748 | 1/20 | 0.61 |
| ▸ | CA6 | P23280 | 1/20 | 0.61 |
| ▸ | CA5A | P35218 | 1/20 | 0.61 |
| ▸ | CA7 | P43166 | 1/20 | 0.61 |
| ▸ | CA9 | Q16790 | 1/20 | 0.61 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.61 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.61 |
| ▸ | RARB | P10826 | 6/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.59 |
| ▸ | MEN1 | O00255 | 1/20 | 0.57 |
| ▸ | RARA | P10276 | 1/20 | 0.57 |
| ▸ | MAPT | P10636 | 1/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Benzoic Acid SCHEMBL28142480 | 0.93 | ESR1 (0.55) | ESR1ESR2CA12CA1CA2 | |
| SCHEMBL44017 | 0.92 | RARB (0.69) | RARBALDH1A1MEN1RARAMAPT | |
| Methyl Alcohol SCHEMBL38654374 | 0.90 | RARB (0.67) | RARBALDH1A1MEN1RARAMAPT | |
| Hydrochloric Acid SCHEMBL6560888 | 0.90 | RARB (0.67) | RARBALDH1A1MEN1RARAMAPT | |
| Ammonia Solution, Strong SCHEMBL9652121 | 0.90 | RARB (0.67) | RARBALDH1A1MEN1RARAMAPT | |
| Bicarbonate SCHEMBL10897348 | 0.88 | ESR1 (0.61) | ESR1ESR2CA2ALDH1A1L3MBTL1 | |
| Bicarbonate SCHEMBL9642429 | 0.88 | ESR1 (0.61) | ESR1ESR2CA2ALDH1A1L3MBTL1 | |
| SCHEMBL900992 | 0.88 | CA2 (0.73) | ESR1ESR2CA12CA1CA2 | |
| Paraben SCHEMBL11510587 | 0.87 | RARB (0.78) | ESR1RARBALDH1A1MEN1RARA | |
| SCHEMBL200372 | 0.86 | RARB (0.79) | RARBALDH1A1MEN1RARAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103443201-B | The polycarbonate-polysiloxane compound that the thermotolerance improved is transparent | SABIC INNOVATIVE PLASTICS IP B.V. (NL) | 2016-06-01 | — | — | CN | disclosed |
| CN-100442148-C | Process for producing toner, and apparatus for modifying surfaces of toner particles | CANON KK (JP) | 2008-12-10 | — | — | CN | disclosed |
| CN-1637632-A | Process for producing toner, and apparatus for modifying surfaces of toner particles | CANON KK (JP) | 2005-07-13 | — | — | CN | disclosed |
| US-4917983-A | Toner for developing an electrostatic latent image comprising linear polyester polymer | KONISHIROKU PHOTO INDUSTRY CO., LTD. (JP) | 1990-04-17 | — | — | US | disclosed |