Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 3/20 | 0.73 |
| ▸ | CA12 | O43570 | 1/20 | 0.73 |
| ▸ | CA1 | P00915 | 1/20 | 0.73 |
| ▸ | CA3 | P07451 | 1/20 | 0.73 |
| ▸ | TYR | P14679 | 1/20 | 0.73 |
| ▸ | DRD1 | P21728 | 1/20 | 0.73 |
| ▸ | CA4 | P22748 | 1/20 | 0.73 |
| ▸ | CA6 | P23280 | 1/20 | 0.73 |
| ▸ | CA5A | P35218 | 1/20 | 0.73 |
| ▸ | CA7 | P43166 | 1/20 | 0.73 |
| ▸ | CA9 | Q16790 | 1/20 | 0.73 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.73 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.73 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.64 |
| ▸ | ESR1 | P03372 | 1/20 | 0.64 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.64 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.56 |
| ▸ | TP53 | P04637 | 1/20 | 0.55 |
| ▸ | TSHR | P16473 | 1/20 | 0.55 |
| ▸ | RARB | P10826 | 3/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Paraben SCHEMBL9244762 | 0.91 | CA12 (0.67) | CA2CA12CA1CA3TYR | |
| SCHEMBL9101705 | 0.91 | CA12 (0.67) | CA2CA12CA1CA3TYR | |
| SCHEMBL70166 | 0.91 | TSHR (0.67) | CA2CA12CA1CA3TYR | |
| Terephthalic Acid SCHEMBL4612225 | 0.91 | TSHR (0.67) | CA2CA12CA1CA3TYR | |
| Hydrochloric Acid SCHEMBL7132238 | 0.88 | TSHR (0.63) | CA2CA12CA1CA3TYR | |
| Terephthalic Acid SCHEMBL10409003 | 0.88 | ESR1 (0.63) | CA2CA12CA1CA3TYR | |
| SCHEMBL2130368 | 0.86 | CA2 (0.73) | CA2CA12CA1CA3TYR | |
| Terephthalic Acid SCHEMBL6692916 | 0.85 | CA2 (1.00) | CA2CA12CA1CA3TYR | |
| Paraben SCHEMBL20500516 | 0.85 | CA2 (1.00) | CA2CA12CA1CA3TYR | |
| Terephthalic Acid SCHEMBL3460105 | 0.85 | CA2 (1.00) | CA2CA12CA1CA3TYR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 26 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3500627-A1 | ADDUCTS AND USES THEREOF | Huntsman Advanced Materials Americas LLC (US) | 2019-06-26 | — | — | EP | disclosed |
| WO-2018035397-A1 | ADDUCTS AND USES THEREOF | HUNTSMAN ADVANCED MATERIALS AMERICAS LLC (US) | 2018-02-22 | — | — | WO | disclosed |
| EP-2726529-A1 | HYBRID EPOXY RESINS | Dow Global Technologies LLC (US) | 2014-05-07 | — | — | EP | disclosed |
| EP-2726530-A1 | HYBRID EPOXY RESIN ADDUCTS | Dow Global Technologies LLC (US) | 2014-05-07 | — | — | EP | disclosed |
| EP-2621994-A1 | EPOXY RESIN COMPOSITIONS | Dow Global Technologies LLC (US) | 2013-08-07 | — | — | EP | disclosed |
| EP-2621992-A2 | EPOXY RESIN ADDUCTS AND THERMOSETS THEREOF | Dow Global Technologies LLC (US) | 2013-08-07 | — | — | EP | disclosed |
| WO-2013055411-A1 | HYBRID EPOXY RESINS | DOW GLOBAL TECHNOLOGIES LLC (US) | 2013-04-18 | — | — | WO | disclosed |
| EP-2563835-A1 | EPOXY POLYCYCLOPENTADIENE COMPOUNDS | Dow Global Technologies LLC (US) | 2013-03-06 | — | — | EP | disclosed |
| WO-2013006250-A1 | HYBRID EPOXY RESIN ADDUCTS | DOW GLOBAL TECHNOLOGIES LLC (US) | 2013-01-10 | — | — | WO | disclosed |
| WO-2012050688-A2 | EPOXY RESIN ADDUCTS AND THERMOSETS THEREOF | DOW GLOBAL TECHNOLOGIES LLC (US) | 2012-04-19 | — | — | WO | disclosed |
| US-6960681-B2 | Guanidinomethyl cyclohexane carboxylic acid ester derivatives | NAGASE CHEMTEX CORPORATION (JP) | 2005-11-01 | — | — | US | disclosed |
| US-20050075402-A1 | Guanidinomethyl cyclohexane carboxylic acid ester derivatives | TEIKOKU CHEMICAL INDUSTRIES CO., LTD. | 2005-04-07 | — | — | US | disclosed |
| US-6831190-B1 | Acts effectively in stomach, the antibacterial activity becomes weak as the compounds moves from duodenum to small intestines; do not have activity against esylhiacori, staphylococcus aureus, methacycline resistant bacterium | TEIKOKU CHEMICAL INDUSTRIES CO., LTD. (JP) | 2004-12-14 | — | — | US | disclosed |
| EP-1449828-A2 | Guanidinomethyl cyclohexane carboxylic acid ester derivatives | Nagase ChemteX Corporation (JP) | 2004-08-25 | — | — | EP | disclosed |
| US-6284791-B1 | USEFUL AS AN ANTI-MICROBIAL AGAINST HELICOBACTER PYLORI | TEIKOKU CHEMICAL INDUSTRIES CO., LTD. (JP) | 2001-09-04 | — | — | US | disclosed |
| EP-0741128-B1 | Sulphuric acid esters of sugar alcohols for the inhibition of the migration and proliferation of smooth muscle cells of the vascular walls | HOFFMANN LA ROCHE (CH) | 2001-06-20 | — | — | EP | disclosed |
| EP-0775692-B1 | GUANIDINOMETHYL CYCLOHEXANE CARBOXYLIC ESTER DERIVATIVE | TEIKOKU CHEM IND CO LTD (JP) | 2000-12-06 | — | — | EP | disclosed |
| EP-0989112-A2 | Intermediates for the preparation of guanidinomethyl cyclohexane carboxylic acid ester derivatives | TEIKOKU CHEMICAL INDUSTRY CO., LTD. (JP) | 2000-03-29 | — | — | EP | disclosed |
| EP-0775692-A1 | GUANIDINOMETHYL CYCLOHEXANE CARBOXYLIC ESTER DERIVATIVE | TEIKOKU CHEMICAL INDUSTRY CO., LTD. (JP) | 1997-05-28 | — | — | EP | disclosed |
| EP-0741128-A2 | Sulphuric acid esters of sugar alcohols for the inhibition of the migration and proliferation of smooth muscle cells of the vascular walls | F. HOFFMANN-LA ROCHE AG (CH) | 1996-11-06 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050075402-A1 | Guanidinomethyl cyclohexane carboxylic acid ester derivatives | GCK, ADCY9, ADCY7 | CA2 454/4885CA12 1533/4885CA1 1488/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.