SCHEMBL10409089

SCHEMBL10409089

C=C(CC)c1ccc2cc(OC)ccc2c1

nearest known ligand 0.56

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 2/20 0.56
CYP1A2 P05177 2/20 0.51
ALDH1A1 P00352 2/20 0.51
HPGD P15428 1/20 0.51
CYP2C19 P33261 1/20 0.51
HSD17B10 Q99714 1/20 0.51
NR1I2 O75469 1/20 0.48
CYP2A6 P11509 1/20 0.47
PLAU P00749 1/20 0.44
AKR1C3 P42330 4/20 0.44
AKR1C2 P52895 4/20 0.44
PTGS1 P23219 2/20 0.44
ABCB11 O95342 1/20 0.44
AKR1C1 Q04828 1/20 0.43
NPC1 O15118 1/20 0.43
PKM P14618 1/20 0.43
RAB9A P51151 1/20 0.43
SMN1; SMN2 Q16637 1/20 0.43
KDM2B Q8NHM5 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9420893 0.86 KDM4E (0.56) KDM4ECYP1A2ALDH1A1HPGDCYP2C19
SCHEMBL5085228 0.83 NR1I2 (0.63) KDM4EALDH1A1HPGDCYP2C19HSD17B10
SCHEMBL9420912 0.79 KDM4E (0.61) KDM4ECYP1A2ALDH1A1HPGDCYP2C19
SCHEMBL6381436 0.79 SMN1; SMN2 (0.53) KDM4ECYP1A2ALDH1A1HPGDHSD17B10
SCHEMBL30436597 0.79 KDM4E (0.61) KDM4ECYP1A2ALDH1A1HPGDCYP2C19
SCHEMBL31427513 0.79 ALDH1A1 (0.69) KDM4ECYP1A2ALDH1A1HPGDCYP2C19
SCHEMBL7173547 0.79 ALDH1A1 (0.69) KDM4ECYP1A2ALDH1A1HPGDCYP2C19
SCHEMBL7806181 0.78 KDM4E (0.59) KDM4ECYP1A2ALDH1A1HPGDCYP2C19
SCHEMBL23019763 0.76 GAA (0.61) KDM4ECYP1A2ALDH1A1HPGDCYP2C19
SCHEMBL6069211 0.76 GAA (0.61) KDM4ECYP1A2ALDH1A1HPGDCYP2C19

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2021257279-A1 REUSABLE FACE MASK IONIC MATERIALS, INC. (US) 2021-12-23 WO disclosed
US-4912274-A Azaphospholenes and use thereof STUDIENGESELLSCHAFT KOHLE MBH (DE) 1990-03-27 US disclosed