Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1I2 | O75469 | 1/20 | 0.63 |
| ▸ | MAPT | P10636 | 2/20 | 0.52 |
| ▸ | MAOA | P21397 | 1/20 | 0.50 |
| ▸ | MAOB | P27338 | 1/20 | 0.50 |
| ▸ | CES2 | O00748 | 1/20 | 0.50 |
| ▸ | CES1 | P23141 | 1/20 | 0.50 |
| ▸ | CA1 | P00915 | 6/20 | 0.48 |
| ▸ | CA2 | P00918 | 6/20 | 0.48 |
| ▸ | CA12 | O43570 | 1/20 | 0.48 |
| ▸ | CA7 | P43166 | 1/20 | 0.48 |
| ▸ | CA9 | Q16790 | 1/20 | 0.48 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.48 |
| ▸ | GSK3B | P49841 | 1/20 | 0.47 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.47 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.47 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.47 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.47 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.47 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.47 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2263489 | 0.83 | NR1I2 (0.42) | NR1I2MAPTMAOAMAOBALDH1A1 | |
| SCHEMBL10409089 | 0.83 | KDM4E (0.56) | NR1I2ALDH1A1SMN1; SMN2KDM4EHPGD | |
| SCHEMBL14407542 | 0.83 | NR1I2 (0.52) | NR1I2MAPTMAOAMAOBCES2 | |
| SCHEMBL13962133 | 0.81 | CA1 (0.50) | NR1I2MAPTMAOAMAOBCA1 | |
| SCHEMBL16795750 | 0.81 | MAPT (0.50) | NR1I2MAPTMAOAMAOBCES2 | |
| SCHEMBL18911078 | 0.81 | NQO1 (0.58) | ALDH1A1PRSS1PRSS2PRSS3PARP10 | |
| SCHEMBL989934 | 0.81 | GSK3B (0.60) | NR1I2MAPTMAOAMAOBCES2 | |
| SCHEMBL8552180 | 0.81 | LMNA (0.51) | NR1I2MAPTMAOAMAOBCES2 | |
| SCHEMBL9336832 | 0.80 | NR1I2 (0.50) | NR1I2MAPTMAOAMAOBCES2 | |
| SCHEMBL6693430 | 0.78 | ALDH1A1 (0.48) | NR1I2ALDH1A1SMN1; SMN2KDM4ETSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3434668-B1 | INDOLO-SUBSTITUTED-PIPERIDINE COMPOUNDS AS ESTROGEN RECEPTOR DEGRADING AGENT | LUOXIN PHARMACEUTICAL SHANGHAI CO LTD (CN) | 2020-08-26 | — | — | EP | disclosed |
| CN-103698456-B | Online detection method for pyrolysis gas-phase components of tobacco additive or tobacco material | SHANGHAI TOBACCO GROUP CO LTD | 2015-07-15 | — | — | CN | disclosed |
| CN-103698456-A | Online detection method for pyrolysis gas-phase components of tobacco additive or tobacco material | SHANGHAI TOBACCO GROUP CO LTD | 2014-04-02 | — | — | CN | disclosed |
| US-20110275826-A1 | CHIRAL LIGANDS | SOLVIAS AG (CH) | 2011-11-10 | — | — | US | disclosed |
| EP-1432416-B1 | AMINOINDAZOLE DERIVATIVES ACTIVE AS KINASE INHIBITORS, PROCESS FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | PFIZER ITALIA SRL (IT) | 2011-01-19 | — | — | EP | disclosed |
| WO-2010072746-A1 | CHIRAL LIGANDS | SOLVIAS AG (CH) | 2010-07-01 | — | — | WO | disclosed |
| EP-2202236-A1 | Chiral ligands | Solvias AG (CH) | 2010-06-30 | — | — | EP | disclosed |
| EP-1658298-B1 | PHOSPHORUS-CONTAINING IMIDAZOLINES AND METAL COMPLEXES THEREOF | SOLVIAS AG (CH) | 2008-03-26 | — | — | EP | disclosed |
| EP-1404650-B1 | CARBOXAMIDE-SUBSTITUTED PHENYLUREA DERIVATIVES AND METHOD FOR PRODUCTION THEREOF AS MEDICAMENTS | SANOFI AVENTIS DEUTSCHLAND (DE) | 2008-02-13 | — | — | EP | disclosed |
| US-20070010493-A1 | Phospinite-imidazolines and metal complexes thereof | SOLVIAS AG (CH) | 2007-01-11 | — | — | US | disclosed |
| EP-1658298-A2 | NOVEL ORGANIC COMPOUNDS AND METAL COMPLEXES | Solvias AG (CH) | 2006-05-24 | — | — | EP | disclosed |
| EP-1191030-B1 | Phosphinite-oxazolines and metal complexes | SOLVIAS AG (CH) | 2005-05-04 | — | — | EP | disclosed |
| WO-2005021562-A2 | PHOSPINITE-IMIDAZOLINES AND METAL COMPLEXES THEREOF | SOLVIAS AG (CH) | 2005-03-10 | — | — | WO | disclosed |
| US-6632954-B2 | Chelate compounds | SOLVIAS AG (CH) | 2003-10-14 | — | — | US | disclosed |
| US-6498256-B2 | CATALYSTS FOR ASYMMETRIC ADDITION REACTIONS, FOR EXAMPLE OF HYDROGEN, TO PROCHIRAL UNSATURATED ORGANIC COMPOUNDS. | SOLVIAS AG (CH) | 2002-12-24 | — | — | US | disclosed |
| US-20020128486-A1 | Phosphinite-oxazolines and metal complexes | PFALTZ ANDREAS (CH) | 2002-09-12 | — | — | US | disclosed |
| US-20020062027-A1 | Phosphinite-oxazolines and metal complexes | SOLVIAS AG (CH) | 2002-05-23 | — | — | US | disclosed |
| EP-1191030-A2 | Phosphinite-oxazolines and metal complexes | Solvias AG (CH) | 2002-03-27 | — | — | EP | disclosed |
| US-4997836-A | Inhibitor of platelet activating factor | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1991-03-05 | — | — | US | disclosed |
| EP-0368670-A1 | Trisubstituted piperazine compounds, their production and use | Takeda Chemical Industries, Ltd. (JP) | 1990-05-16 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110275826-A1 | CHIRAL LIGANDS | C3AR1, C1S, C1R | NR1I2 579/4885MAPT 4823/4885MAOA 2207/4885 |
| US-20020062027-A1 | Phosphinite-oxazolines and metal complexes | OXER1, OXGR1, H1-4 | NR1I2 38/4885MAPT 4862/4885MAOA 2752/4885 |
| US-20070010493-A1 | Phospinite-imidazolines and metal complexes thereof | H1-0, H1-2, H1-3 | NR1I2 137/4885MAPT 4844/4885MAOA 2871/4885 |
| US-20020128486-A1 | Phosphinite-oxazolines and metal complexes | OXER1, OXGR1, H1-4 | NR1I2 38/4885MAPT 4862/4885MAOA 2752/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.