Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.56 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.51 |
| ▸ | HPGD | P15428 | 1/20 | 0.51 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.51 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.51 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.47 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.47 |
| ▸ | PLAU | P00749 | 1/20 | 0.44 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.44 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.44 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.44 |
| ▸ | HSD17B1 | P14061 | 1/20 | 0.42 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 2/20 | 0.41 |
| ▸ | NQO2 | P16083 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10409089 | 0.86 | KDM4E (0.56) | KDM4ECYP1A2ALDH1A1HPGDCYP2C19 | |
| SCHEMBL14407542 | 0.83 | NR1I2 (0.52) | KDM4EALDH1A1HPGDCYP2C19HSD17B10 | |
| SCHEMBL16795640 | 0.80 | CES2 (0.56) | NPC1MAOARAB9ASMN1; SMN2MEN1 | |
| SCHEMBL9420912 | 0.79 | KDM4E (0.61) | KDM4ECYP1A2ALDH1A1HPGDCYP2C19 | |
| SCHEMBL30436597 | 0.79 | KDM4E (0.61) | KDM4ECYP1A2ALDH1A1HPGDCYP2C19 | |
| SCHEMBL7806181 | 0.78 | KDM4E (0.59) | KDM4ECYP1A2ALDH1A1HPGDCYP2C19 | |
| SCHEMBL14072806 | 0.77 | RELA (0.52) | KDM4ECYP1A2ALDH1A1HPGDCYP2C19 | |
| SCHEMBL16795935 | 0.75 | ALDH1A1 (0.48) | KDM4EALDH1A1NQO2CYP3A4SMN1; SMN2 | |
| SCHEMBL16795704 | 0.74 | CYP2C9 (0.55) | CYP1A2ALDH1A1HPGDCYP2C19HSD17B10 | |
| SCHEMBL11803762 | 0.74 | KDM4E (0.54) | KDM4ECYP1A2ALDH1A1HPGDCYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5286902-A | Process for preparation of 2-(6-methoxy-2-naphthyl)propionic acid and intermediates therefor utilizing 2,6-diisopropylnaphthalene | KOCH INDUSTRIES, INC. (US) | 1994-02-15 | — | — | US | disclosed |