Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | APEX1 | P27695 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | TSPO | P30536 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10410576 | 0.81 | SMN1; SMN2 (0.41) | POLBMAPTKMT2ANPSR1 | |
| SCHEMBL10821263 | 0.79 | HSP90AA1 (0.38) | TDP1MAPTGAAHTTKMT2A | |
| SCHEMBL9688953 | 0.78 | AKR1B1 (0.42) | POLBAPEX1TDP1MAPTGAA | |
| SCHEMBL9689265 | 0.77 | HTR1A (0.48) | — | |
| SCHEMBL9688738 | 0.72 | HTR1A (0.43) | — | |
| SCHEMBL9688885 | 0.67 | TAAR1 (0.39) | APEX1TDP1MAPTKMT2A | |
| SCHEMBL28176890 | 0.66 | METAP2 (0.36) | MAPT | |
| SCHEMBL9596859 | 0.65 | MEN1 (0.68) | MAPTKMT2ANPSR1 | |
| SCHEMBL9687997 | 0.65 | OPRK1 (0.45) | POLBMAPTHTT | |
| SCHEMBL5164427 | 0.62 | POLB (0.46) | POLBAPEX1TDP1MAPTTSPO |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4958026-A | HYPOTENSIVE AGENTS | SCHERING AKTIENGESLLSCHAFT (DE) | 1990-09-18 | — | — | US | disclosed |