Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.54 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.54 |
| ▸ | MEN1 | O00255 | 1/20 | 0.54 |
| ▸ | LMNA | P02545 | 1/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.54 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.54 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.45 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.45 |
| ▸ | DRD2 | P14416 | 1/20 | 0.44 |
| ▸ | DRD4 | P21917 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | MGLL | Q99685 | 1/20 | 0.44 |
| ▸ | RECQL | P46063 | 1/20 | 0.43 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.43 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10409232 | 0.87 | MAPK1 (0.55) | TSHRMAPK1MEN1LMNAKMT2A | |
| SCHEMBL10410773 | 0.80 | KDM4E (0.50) | ALDH1A1KDM4EDRD2DRD4CHRM2 | |
| SCHEMBL6609510 | 0.78 | S1PR5 (0.53) | TSHRMEN1LMNAKMT2ASMN1; SMN2 | |
| SCHEMBL2962712 | 0.76 | FUCA1 (0.58) | TSHR | |
| SCHEMBL10409277 | 0.75 | HTT (0.57) | LMNAKMT2ASMN1; SMN2ALDH1A1KDM4E | |
| Ambasilide SCHEMBL427931 | 0.74 | HSD11B1 (0.53) | TSHRMAPK1MEN1LMNAKMT2A | |
| Ambasilide SCHEMBL246531 | 0.74 | HSD11B1 (0.53) | TSHRMAPK1MEN1LMNAKMT2A | |
| SCHEMBL17953046 | 0.74 | KDM4E (0.61) | TSHRMAPK1MEN1LMNAKMT2A | |
| SCHEMBL22702112 | 0.73 | CA12 (0.54) | LMNAL3MBTL1ALDH1A1KDM4ENPC1 | |
| SCHEMBL29804524 | 0.73 | CA12 (0.54) | LMNAL3MBTL1ALDH1A1KDM4ENPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4959373-A | Bispidine derivatives as class III antiarrhythmic agents | BASF AKTIENGESELLSCHAFT (DE) | 1990-09-25 | — | — | US | disclosed |