Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 1/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.56 |
| ▸ | LMNA | P02545 | 2/20 | 0.56 |
| ▸ | MAPT | P10636 | 1/20 | 0.56 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.52 |
| ▸ | NPC1 | O15118 | 1/20 | 0.51 |
| ▸ | GALR3 | O60755 | 1/20 | 0.51 |
| ▸ | RAB9A | P51151 | 1/20 | 0.51 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.51 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.51 |
| ▸ | PKM | P14618 | 2/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.50 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.48 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.48 |
| ▸ | ATM | Q13315 | 1/20 | 0.48 |
| ▸ | ACHE | P22303 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9523745 | 0.86 | HTT (0.57) | HTTALDH1A1SMN1; SMN2LMNAMAPT | |
| SCHEMBL10410783 | 0.85 | HTT (0.56) | HTTALDH1A1SMN1; SMN2LMNAMAPT | |
| SCHEMBL10410773 | 0.84 | KDM4E (0.50) | ALDH1A1MAPTKDM4ECHRM2CHRM3 | |
| SCHEMBL10409322 | 0.80 | HTT (0.50) | HTTALDH1A1SMN1; SMN2LMNAMAPT | |
| SCHEMBL6609510 | 0.77 | S1PR5 (0.53) | ALDH1A1SMN1; SMN2LMNAKDM4EKMT2A | |
| SCHEMBL10409233 | 0.75 | TSHR (0.54) | ALDH1A1SMN1; SMN2LMNAKDM4ENPC1 | |
| SCHEMBL10409271 | 0.75 | ALDH1A1 (0.60) | HTTALDH1A1SMN1; SMN2LMNAMAPT | |
| SCHEMBL2962712 | 0.75 | FUCA1 (0.58) | SIGMAR1ACHE | |
| SCHEMBL17953046 | 0.73 | KDM4E (0.61) | ALDH1A1SMN1; SMN2LMNAKDM4ECHRM2 | |
| SCHEMBL17055124 | 0.72 | CA1 (0.56) | HTTALDH1A1SMN1; SMN2LMNATDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4959373-A | Bispidine derivatives as class III antiarrhythmic agents | BASF AKTIENGESELLSCHAFT (DE) | 1990-09-25 | — | — | US | disclosed |