Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | GLA | P06280 | 1/20 | 0.37 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.36 |
| ▸ | GABRB2 | P47870 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 3/20 | 0.35 |
| ▸ | DPP4 | P27487 | 1/20 | 0.35 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.34 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.34 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.34 |
| ▸ | AAK1 | Q2M2I8 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | HTR2A | P28223 | 1/20 | 0.33 |
| ▸ | HTR2C | P28335 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31310646 | 0.85 | KDM4E (0.39) | KDM4EGLAMAPTSLC6A2SLC6A4 | |
| SCHEMBL12320858 | 0.84 | GABRA1 (0.36) | KDM4EGLAGABRA1GABRB2MAPT | |
| SCHEMBL19410653 | 0.83 | AAK1 (0.38) | KDM4EGLAMAPTSLC6A2SLC6A4 | |
| SCHEMBL2262110 | 0.79 | KDM4E (0.34) | KDM4EGLAMAPTSLC6A2SLC6A4 | |
| SCHEMBL2339661 | 0.79 | MAPT (0.41) | KDM4EGABRA1GABRB2MAPTALDH1A1 | |
| SCHEMBL30227313 | 0.79 | MAPT (0.41) | KDM4EGABRA1GABRB2MAPTALDH1A1 | |
| SCHEMBL9069659 | 0.79 | ALDH1A1 (0.43) | KDM4EGABRA1GABRB2MAPTMEN1 | |
| SCHEMBL12204983 | 0.79 | ALOX15 (0.39) | GABRA1GABRB2MAPTDPP4 | |
| Ammonia Solution, Strong SCHEMBL20529675 | 0.78 | KDM4E (0.36) | KDM4EGLAMAPTDPP4SLC6A2 | |
| SCHEMBL22715284 | 0.78 | DPP4 (0.40) | GABRA1GABRB2MAPTDPP4ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4925984-A | REACTION WITH BROMINE IN SOLUTION | ETHYL CORPORATION (US) | 1990-05-15 | — | — | US | disclosed |