Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 1/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.56 |
| ▸ | LMNA | P02545 | 2/20 | 0.56 |
| ▸ | MAPT | P10636 | 1/20 | 0.56 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.52 |
| ▸ | NPC1 | O15118 | 1/20 | 0.51 |
| ▸ | GALR3 | O60755 | 1/20 | 0.51 |
| ▸ | RAB9A | P51151 | 1/20 | 0.51 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.51 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.51 |
| ▸ | PKM | P14618 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.50 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.48 |
| ▸ | ACHE | P22303 | 1/20 | 0.48 |
| ▸ | BLM | P54132 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10409277 | 0.86 | HTT (0.57) | HTTALDH1A1SMN1; SMN2LMNAMAPT | |
| SCHEMBL10410783 | 0.85 | HTT (0.56) | HTTALDH1A1SMN1; SMN2LMNAMAPT | |
| SCHEMBL9522199 | 0.84 | KDM4E (0.50) | ALDH1A1LMNAKDM4E | |
| SCHEMBL9521748 | 0.83 | KDM4E (0.49) | ALDH1A1SMN1; SMN2LMNAKDM4ECHRM2 | |
| SCHEMBL10409322 | 0.80 | HTT (0.50) | HTTALDH1A1SMN1; SMN2LMNAMAPT | |
| SCHEMBL10409271 | 0.75 | ALDH1A1 (0.60) | HTTALDH1A1SMN1; SMN2LMNAMAPT | |
| SCHEMBL17953046 | 0.73 | KDM4E (0.61) | ALDH1A1SMN1; SMN2LMNAKDM4ECHRM2 | |
| SCHEMBL17055124 | 0.72 | CA1 (0.56) | HTTALDH1A1SMN1; SMN2LMNATDP1 | |
| SCHEMBL17444701 | 0.72 | KCNH2 (0.73) | HTTALDH1A1SMN1; SMN2LMNAMAPT | |
| SCHEMBL8551099 | 0.72 | MAPT (0.66) | ALDH1A1SMN1; SMN2LMNAMAPTTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0308843-B1 | Bispidin derivatives as class III antiarrhythmics | BASF AG (DE) | 1993-12-15 | — | — | EP | disclosed |
| EP-0308843-A2 | Bispidin derivatives as class III antiarrhythmics | BASF Aktiengesellschaft (DE) | 1989-03-29 | — | — | EP | disclosed |