Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.60 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.52 |
| ▸ | HTT | P42858 | 2/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.51 |
| ▸ | LMNA | P02545 | 3/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.51 |
| ▸ | TSHR | P16473 | 1/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.51 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 2/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | MGLL | Q99685 | 1/20 | 0.48 |
| ▸ | BLM | P54132 | 1/20 | 0.48 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10409232 | 0.81 | MAPK1 (0.55) | ALDH1A1KMT2AL3MBTL1SMN1; SMN2LMNA | |
| SCHEMBL9521948 | 0.76 | ALDH1A1 (0.50) | ALDH1A1KMT2AL3MBTL1SMN1; SMN2LMNA | |
| SCHEMBL9521359 | 0.76 | KMT2A (0.58) | ALDH1A1KMT2AL3MBTL1HTTSMN1; SMN2 | |
| Ambasilide SCHEMBL246531 | 0.76 | HSD11B1 (0.53) | ALDH1A1KMT2AL3MBTL1SMN1; SMN2LMNA | |
| SCHEMBL9521802 | 0.76 | SIGMAR1 (0.50) | SIGMAR1 | |
| Ambasilide SCHEMBL427931 | 0.76 | HSD11B1 (0.53) | ALDH1A1KMT2AL3MBTL1SMN1; SMN2LMNA | |
| SCHEMBL10410350 | 0.76 | GAA (0.54) | ALDH1A1KMT2AL3MBTL1HTTSMN1; SMN2 | |
| SCHEMBL17444586 | 0.75 | KMT2A (0.68) | ALDH1A1RXFP1KMT2AL3MBTL1HTT | |
| SCHEMBL9523745 | 0.75 | HTT (0.57) | ALDH1A1KMT2AL3MBTL1HTTSMN1; SMN2 | |
| SCHEMBL10409277 | 0.75 | HTT (0.57) | ALDH1A1KMT2AHTTSMN1; SMN2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4959373-A | Bispidine derivatives as class III antiarrhythmic agents | BASF AKTIENGESELLSCHAFT (DE) | 1990-09-25 | — | — | US | disclosed |